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Industry Insights

“Mastermind” Scientists Help Diagnose Rare Diseases
Industry Insight

The Rare Genomics Institute announced on Rare Disease Day 2019 that they had used the Mastermind Genomic Search Engine, a clinical decision support tool by Genomenon, to diagnose a rare disease patient. We spoke to Mark Kiel, MD, PhD, Founder and Chief Science Officer at Genomenon and Romina Ortiz, COO at the Rare Genomics Institute, to learn more about the application of this technology in rare diseases.

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Tiny Protein Has Huge Potential in CRISPR
Industry Insight

Last year the smallest CRISPR protein, Cas14 was discovered. We spoke to the scientists that made the discovery, Lucas Harrington, at Mammoth Biosciences, to learn more about Cas14.

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Automated Microfluidic Systems for Gene Editing
Industry Insight

Recently, Oxford Genetics and Sphere Fluidics announced a multi-partner collaboration to expedite the development of automated microfluidic systems for rapid and high-throughput gene editing in mammalian cells. We spoke with Emily Leproust, PhD, CEO of Twist Biosciences, and other collaborators from the partnership to discuss the background of this announcement and the need for automated systems in gene editing.

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Take a Good Book Around
Industry Insight

Our recent social media poll on "book recommendations for scientists" provided an incredible response. We decided to collate this information and give you the perfect excuse to treat yourself to a new read. Enjoy!

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Is Off-the-Shelf Immunotherapy the Way Forward?
Industry Insight

An “off-the-shelf” immuno-oncology product has been developed whereby T cells are derived from healthy donors, bypassing limitations related to high pricing and limited market access.

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FISH Probes Approved for Targeted Genome Analysis in Cancer
Industry Insight

Recently, the FDA granted de novo classification for eight fluorescence in situ hybridisation (FISH) probes for myelodysplastic syndromes and acute myeloid leukaemia. We spoke with Steve Chatters, Director of Medical Affairs at Oxford Gene Technology, to learn more about the application of FISH probes in modern medicine.

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Supporting Drug Discovery with Cell-centered Models of the Immune System
Industry Insight

Many biological processes, specifically the immune system, operate at a cellular level. CytoReason have harnessed this knowledge to build computational, high-resolution, mechanistic models for a range of diseases that enables better discovery and validation of drug targets.

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Antibody Cascade Design Key to Customizing Success
Industry Insight

We caught up with Abcam's Head of Custom Services, Jamie Campbell, who recently presented at the Protein & Antibody Engineering Summit, Europe. Jamie discusses the company’s approach to discovering antibodies – key reagents in drug discovery, in vitro diagnostics and therapeutics.

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Identifying a Microbial Needle in a Sample Haystack
Industry Insight

We spoke to Dr Jack Regan, CEO of LexaGene, a biotechnology company developing a fully automated pathogen detection platform, and inventor of their patented microfluidic system, about the foundations and evolution of the system, and the future outlook for the tool.

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Deciphering RNA to Predict if a Patient Will Respond to a Targeted Drug
Industry Insight

We recently spoke to Alif Saleh, CEO of Scipher Medicine to learn how RNA data from a patient’s blood sample can be used to determine the underlying molecular processes driving a disease, and establish how well a patient will respond to a particular therapy.

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