Genomic Analyses of Hormone Signaling and Gene Regulation
Conference Recording Feb 01, 2013
About the Speaker
Dr. Edwin Cheung is a Principal Investigator at the Genome Institute of Singapore and an Adjunct Associate Professor at the Department of Biochemistry, National University of Singapore. His lab is focused on elucidating the molecular basis by which steroid hormones control the development and progression of human cancers. Specifically, he is interested in applying modern biological approaches to define the rules governing signal-regulated gene expression by steroid hormones (estrogen and androgen), their cognate receptors and associated cofactors.AbstractIn my talk, I will show how my lab has applied novel high-throughput sequencing technologies to elucidate the chromatin organization of cancer cells upon hormone signaling, as well as the identification and characterization of novel factors required for nuclear hormone receptor transcriptional activity.