Mikael Kubista, PhD profile page

In this webinar, our expert speaker will share insights on optimizing PCR performance for applications within cell and gene therapy development, including biodistribution, transgene expression, viral shedding and cellular kinetics.

In our second episode of the New Frontiers in PCR Technologies Series, join a panel of industry experts as they discuss the future of dPCR and qPCR in healthcare and research.

In our first episode of the New Frontiers in PCR Technology Series, join an exclusive Ask Me Anything with Professor Mikael Kubista. Discover how PCR is evolving with next-generation sequencing, CRISPR and microfluidics.

This one-day online event will feature short talks covering recent innovations in research and technology in the cell and gene therapy domain. Our expert panel of presenters will address key advances across the entire R&D pipeline, from pre-clinical work right through to bioprocessing and manufacturing.

In this webinar, our panel of industry experts will share insights on the molecular and immunodiagnostics market by looking at the external factors which will have the most significant impact in the next five years.

As a cornerstone of genetic analysis in biological research, quantitative PCR (qPCR) and digital PCR (dPCR) are the most sensitive molecular methods to analyze nucleic acids and play a key role in the development of cell and gene therapies (CGT).

These tools are widely used during CGT development for example in biodistribution, pharmacokinetics and pharmacodynamics of the investigational lead molecule. But many samples, including tissues rich in nucleases, lipids and other inhibiting substances and target molecules that are short or contain modified bases, can be challenging to work with. For these types of samples, assay design using advanced strategies, concentration standards, spike-in controls and validated normalization is key for reliable analyses.

In this webinar, Dr. Kubista will present strategies for implementing reliable qPCR and dPCR analysis in CGT development while highlighting best practices for adhering to MIQE and dMIQE guidelines and the recently released ISO standard, ISO 20395:2019.