T cells play a pivotal role in adaptive immune responses such as pathogen elimination and tumor immunosurveillance, via an intricate signaling mechanism

Modulating T cell receptor (TCR) engagement and signaling pathways is therefore highly relevant to several therapeutic areas, including cancer immunotherapy, adoptive cell therapy and vaccine development.

The development of drugs and therapies regulating TCR activity requires rapid assays to profile T cell function and health.

Download this application note to learn about a novel assay that was used to simultaneously evaluate:

• T cell activation markers
• Cell proliferation
• Cytokines