As a result of persistent transmission, there are now several mutational variants of SARS-CoV-2, including B.1.1.7 (alpha), B.1.351 (beta), P.1 (gamma), and B.1.617.2 (delta). These variants have emerged and rapidly changed the viral dynamics, thus threatening ongoing public health efforts to limit the transmission of SARS-CoV-2. The development of next-generation sequencing protocols and the rapid sharing of viral genomic data via the Global Initiative on Sharing All Influenza Data (GISAID) has enabled the tracking of SARS-CoV-2 evolution in real-time.
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