Incorporating CCS Values to Enable 4-Dimensional Annotation of Metabolic Features

In metabolomics, the reliable annotation of metabolites for LC-MS/MS based data is essential and requires the adept combination of many parameters. One of the ways this can be supported is through the use of trapped ion mobility spectrometry (TIMS) data, using CCS values to enable 4D annotation.

Download this whitepaper to discover how an approach utilizing TIMS data can improve the annotation of metabolites, showing:

• High reproducibility of CCS values
• Cleaner MS/MS spectra 
• Improved identification in small molecule workflows