The Need for Speed
Infographic Dec 14, 2016
Accelerating the drug discovery process is a key priority for pharmaceutical businesses around the world and the initial screening of large compound libraries continues to be a critical first step. New technologies that offer a competitive edge are greatly sought after – whether that comes in the form of more information, faster screening or deeper understanding.
Mass spectrometry has significant potential to add value to drug discovery research, and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF) has emerged as a powerful technique that ticks all the boxes for a new high-throughput screening methodology to increase productivity while reducing costs and waste within the pharmaceutical setting.
The MALDI PharmaPulse (Bruker Daltonics) can achieve speeds of less than 1 second per sample, which equates to an ability to analyze more than 121,000 samples per day. MALDI-TOF is considerably faster than early MS techniques, such as multiplexed liquid chromatography (LC)-MS technology and Solid Phase Extraction (SPE) methods, which have cycle times of up to 30 seconds and around 10 seconds per sample respectively and are considered too slow for routine HTS.
Data integrity and correct data governance has been brought into the spotlight by regulators in recent years. Having your data systems inspected can be a stressful and scary experience, but things will go smoothly if prior steps are taken to ensure your data systems are up to scratch before the auditors take a look. In this infographic, we look at the key steps you should take to prepare your data for inspection.READ MORE
Like what you just read? You can find similar content on the communities below.Analysis & Separations Applied Sciences Biopharma Cancer Research Cell Science Diagnostics Drug Discovery Informatics Proteomics & Metabolomics Neuroscience Immunology & Microbiology
To personalize the content you see on Technology Networks homepage, Log In or Subscribe for FreeLOGIN SUBSCRIBE FOR FREE