The Need for Speed
Infographic Dec 14, 2016
Accelerating the drug discovery process is a key priority for pharmaceutical businesses around the world and the initial screening of large compound libraries continues to be a critical first step. New technologies that offer a competitive edge are greatly sought after – whether that comes in the form of more information, faster screening or deeper understanding.
Mass spectrometry has significant potential to add value to drug discovery research, and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF) has emerged as a powerful technique that ticks all the boxes for a new high-throughput screening methodology to increase productivity while reducing costs and waste within the pharmaceutical setting.
The MALDI PharmaPulse (Bruker Daltonics) can achieve speeds of less than 1 second per sample, which equates to an ability to analyze more than 121,000 samples per day. MALDI-TOF is considerably faster than early MS techniques, such as multiplexed liquid chromatography (LC)-MS technology and Solid Phase Extraction (SPE) methods, which have cycle times of up to 30 seconds and around 10 seconds per sample respectively and are considered too slow for routine HTS.
Air Quality MonitoringInfographic
The quality of the air we breathe is of concern to many, as are the negative impacts that pollutants can have on health in the short term and the lasting effects. Many of us have the potential to come into contact with air contaminants in our day to day lives, so it is vital that efficient monitoring measures are in place to keep us from harm.READ MORE
Discovery vs Targeted ProteomicsInfographic
Currently, modern proteomics research using Mass Spectrometry (MS) is split between discovery and targeted assays. This infographic includes workflows for the two techniques and will examine the advantages and disadvantages of each method. Finally, common applications of each technology will be explored, and we will look to a future where the division between targeted and discovery methods might not even be required.
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