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CRISPR Could Restore Effectiveness of Lung Cancer Treatment
NewsThe CRISPR-Cas9 gene editing system may be able to restore the effectiveness of first-line chemotherapies used to treat lung cancer by deleting or "knocking out" a gene in cancer tumors that helps the tumors develop resistance to the drugs.
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Salmon's Critical Sense of Smell in Danger
News Dec 19, 2018A powerful sense of smell is critical for salmon to avoid predators, find prey and find their way home to spawn, but it might be in trouble as carbon emissions continue to be absorbed by our ocean.
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A Way to Visualize a Genetic Mutation
News Dec 19, 2018A team of scientists has developed a method that yields, for the first time, visualization of a gene amplifications and deletions known as copy number variants in single cells.
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Patient-specific Organoid Models Appendix Cancer Treatment
News Dec 19, 2018Patient-specific tumor ‘organoid’ models have been developed, to identify the most effective treatment for each tumor.
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Cervical Cancer Test Has 100% Detection Rate
News Dec 18, 2018A new test for cervical cancer was found to detect all of the cancers in a randomised clinical screening trial of 15,744 women, outperforming both the current Pap smear and human papillomavirus (HPV) test at a reduced cost, according to a study led by Queen Mary University of London.
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Pathological Tau Accumulates More in Excitatory, than Inhibitory, Neurons
News Dec 18, 2018Better tactics for detecting, preventing and treating Alzheimer’s disease depend on a clearer understanding of cellular-level changes in the minds of patients, and a new study has uncovered novel details about the vulnerability of one type of brain cell.
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New Strains of Hepatitis C Found in Africa
News Dec 18, 2018Three new strains of hepatitis C have been found circulating in the general population in sub-Saharan Africa, suggesting that certain antiviral drugs currently used in the West may not be as effective against the new strains.
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Compound Blocks Common Genetic Cause of ALS & Frontotemporal Dementia
News Dec 18, 2018Writing in the journal Cell Chemical Biology, Scripps Research chemist Matthew Disney, PhD, and colleagues describe a new compound that blocks the most common genetic cause of both familial ALS and frontotemporal dementia.
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Immune System Kept in Check by Protein Police
News Dec 18, 2018Researchers learn how a key transcription factor helps regulate the immune system and could be critical to understanding autoimmune disease and cancer immunosuppression.
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A Killer on Your Skin
News Dec 17, 2018Staphylococcus epidermidis is an ubiquitous colonizer of healthy human skin, but it is also a notorious source of serious nosocomial infections. Now, a new machine learning technique will help predict the risk of developing a serious, and possibly life-threatening S. epidermidis infection.
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Roots of Neuropsychiatric Risk in the Developing Brain
News Dec 14, 2018The most comprehensive genomic analysis of the human brain ever undertaken has revealed new insights into the changes it undergoes through development, how it varies among individuals, and the roots of neuropsychiatric illnesses such as autism spectrum disorders and schizophrenia.
