New Cause of Hypertrophic Cardiomyopathy Discovered
A research team has identified a new gene as a cause of an inherited heart condition that affects one in 500 people.
Exploring the Evolution of the Human Growth Hormone Receptor Gene
Research has shown that a variant of the human growth hormone receptor gene (GHRd3), may help people survive in situations where resources are scarce or unpredictable.
Origin and Legacy of the Etruscans
A new study by a team of scholars from Germany, Italy, USA, Denmark and the UK, sheds light on the origin and legacy of the enigmatic Etruscans with genome-wide data from 82 ancient individuals from central and southern Italy, spanning 800 BCE to 1000 CE.
Combining Complex Data To Provide New Insights Into Cancer Evolution
For advanced cancers, integrated DNA analyses may help pinpoint overlooked mechanisms that cancer cells use to metastasize, which may be promising targets for therapy development.
Team Plans To Target Oncogene To Selectively Kill Breast Cancer Cells
A research project has been awarded a Breast Cancer Research Program Breakthrough grant from the US Department of Defense and aims to bring novel therapies from the laboratory bench to the help of patients suffering from metastatic breast cancer.
Analysis of Ancient DNA Reveals Brutal Politics of Medieval Spain
Researchers have published the genome sequence of a unique individual from Islamic medieval Spain. The results have shed light on a brutal event that took place.
Reducing Cattle Pregnancy Loss With Genome Editing Technology
A new project will evaluate various aspects of a developing pregnancy in cattle applying genetic knockout technology.
Antibody-Producing B Cells May Have Predetermined Fates
A protein called Oct2 has been identified as the master regulator behind the development of antibody-producing cells. The findings may help understand how certain cancers arise.
Estrogen Receptor Provides Clues To Overcome Resistance to Anticancer Drugs
Estrogen receptor α (ERα) plays a key role in several breast cancers. New research in Cell reports that in addition to its activity in the nucleus, it can also help cancer cells overcome anticancer mechanisms and develop resistance to treatment.
AI Identifies New Drug Combo for Aggressive Childhood Brain Cancer
Scientists have used tools enhanced with AI to successfully propose a new combination of drugs for use against an incurable childhood brain cancer.