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What Can Salad Dressing Tell Us About Cancer? Think Oil & Vinegar
What Can Salad Dressing Tell Us About Cancer? Think Oil & Vinegar
News   Sep 21, 2018

Researchers led by St. Jude Children's Research Hospital scientists have identified another way the process that causes oil to form droplets in water may contribute to solid tumors, such as prostate and breast cancer.

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Party 'Pus: Ecstasy Makes Octopuses More Social
Party 'Pus: Ecstasy Makes Octopuses More Social
News   Sep 21, 2018

When people take MDMA, the drug popularly known as ecstasy, a rush of serotonin, dopamine, and oxytocin makes people more interested than they would normally be in connecting and sharing with other people. Now, researchers have made the surprising discovery that a species of octopus considered to be asocial responds to MDMA in the same way.

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Unprecedented View of Gene Therapy Virus
Unprecedented View of Gene Therapy Virus
News   Sep 21, 2018

Using cryo-electron microscopy, scientists have obtained an unprecedented view of a gene-delivery virus, paving the way for further development of improved gene therapies.

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Decoding the Structure of an RNA-Based CRISPR System
Decoding the Structure of an RNA-Based CRISPR System
News   Sep 21, 2018

Over the past several years, CRISPR-Cas9 has moved beyond the lab bench and into the public zeitgeist. Now, scientists from the Salk Institute are reporting for the first time the detailed molecular structure of CRISPR-Cas13d, a promising enzyme for emerging RNA-editing technology.

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Epigenetic Signature May Help People Stay Ahead of IBD
Epigenetic Signature May Help People Stay Ahead of IBD
News   Sep 21, 2018

In treating inflammatory bowel disease (IBD), physicians can have a hard time telling which newly diagnosed patients have a high risk of severe inflammation or what therapies will be most effective. Now researchers report finding an epigenetic signature in patient cells that appears to predict inflammation risk in a serious type of IBD called Crohn’s disease.

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Therapeutic RNAs get Helping Hand from Green Tea Compound
Therapeutic RNAs get Helping Hand from Green Tea Compound
News   Sep 20, 2018

An antioxidant in green tea called epigallocatechin gallate has been found to have a surprising use: sneaking therapeutic RNAs into cells.

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Genetic Similarities Found Across Multiple Cancer Types
Genetic Similarities Found Across Multiple Cancer Types
News   Sep 20, 2018

Study could lead to new treatments for advanced epithelial cancers such as lung and prostate cancers.

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Protein Curbs Obesity Through Our Gut Bacteria
Protein Curbs Obesity Through Our Gut Bacteria
News   Sep 20, 2018

Scientists from the UNC School of Medicine discovered that the anti-inflammatory protein NLRP12 normally helps protect mice against obesity and insulin resistance when they are fed a high-fat diet. The researchers also reported that the NLRP12 gene is underactive in people who are obese, making it a potential therapeutic target for treating obesity and diabetes.

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Snooker in the Living Cell
Snooker in the Living Cell
News   Sep 20, 2018

The spatial and temporal dynamics of proteins or organelles plays a crucial role in controlling various cellular processes and in development of diseases. However, acute control of activity at distinct locations within a cell cannot be achieved. A new chemo-optogenetic method enables tunable, reversible, and rapid control of activity at multiple subcellular compartments within a living cell.

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How the Cell Copes With Stress
How the Cell Copes With Stress
News   Sep 20, 2018

Researchers from the Department of Biochemistry and Molecular Biology at the UAB and from the United Kingdom, for the first time describe the mechanism used by cells to optimise protein production in stressful situations through the altering of tRNA abundance.

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