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Lungfish Genome Reveals How Aquatic Vertebrates Conquered Land
News Jan 18, 2021A team of scientists has broken a new record for sequencing the largest animal genome to date – the Australian lungfish, one of the few living relatives of the first land vertebrates.
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Rapid Blood Test Identifies COVID-19 Patients at High Risk of Severe Disease
News Jan 18, 2021Scientists have shown that a relatively simple and rapid blood test that measures levels of mitochondrial DNA can predict which patients with COVID-19 are at highest risk of severe complications or death.
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Tracking AAV Gene Transfer Vector Biodistribution
News Jan 18, 2021The biodistribution of adeno-associated virus (AAV) gene transfer vectors can be measured in nonhuman primates using a new method. The method quantifies whole-body and organ-specific AAV capsids from 1 to 72 hours after administration.
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Upscaling "Dinner" Could Improve Aquaculture Success
News Jan 18, 2021Scientists have created larger-than-usual strains of zooplankton — which are used in fish nurseries — by creating mutations with a heavy ion beam. The new strains of zooplankton could contribute to improving the survival rate and optimizing the growth of juvenile fish in aquaculture.
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Targeting the Circadian Rhythm Regulator CRY-1 in Prostate Cancer
News Jan 18, 2021A regulator of circadian rhythms, known as CRY-1 has been shown to promote tumor progression by altering DNA repair.
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Test Can Quickly Identify Pneumonia in Patients With Severe COVID-19
News Jan 15, 2021Researchers have developed a DNA test to quickly identify secondary infections in COVID-19 patients, who have double the risk of developing pneumonia while on ventilation than non-COVID-19 patients.
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Reverse Engineering Highly Detailed Models of Chromosomes
News Jan 15, 2021Researchers at the University of Illinois Chicago report on a computational technique that uses heat map data to reverse engineer highly detailed models of chromosomes.
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Mutations in Little-Studied Gene Regions May Play Role in Autism
News Jan 15, 2021Mutations that occur in certain DNA regions, called tandem repeats, may play a significant role in autism spectrum disorders, according to new research.
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Drug Combo for Rare Form of Cancer Shows Promise in Cell-Based Study
News Jan 15, 2021A rare form of lymphoma called Waldenström macroglobulinemia (WM), currently has no known cure and only one FDA-approved treatment. Researchers have now targeted specific cell proteins that control DNA information using inhibitors, that were effective in reducing the growth of the cancer cells. When combined with a third drug the combination was even more successful at killing the WM cancer cells.
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Cancer Researchers Reveal How Mutations in a Single Gene Can Cause Different Diseases
News Jan 15, 2021Researchers report that they have solved a long-standing question of how various types of mutations in a single gene can cause different types of disease. Their findings were published in Life Science Alliance.
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