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TGen Launches Center for Rare Childhood Disorders

Research efforts focused on changing the lives of countless undiagnosed children.
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Horizon and NIH CRM Collaborate to Apply rAAV Genome Editing to Stem Cells

Collaboration aims to understand the effects of specific gene sequences on stem cell differentiation.
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Non-Genotoxic Carcinogen Exposure Induces Defined Changes in the 5-Hydroxymethylome

In a genome wide study Meehan, Moggs and MARCAR co-authors examined 5mC and 5hmC profiles of liver in control and phenobarbital treated mice. They observe dynamic and reciprocal changes in the 5mC/5hmC patterns over genes promoters that are transcriptionally up-regulated.
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Tissue of Origin Determines Cancer-associated CpG Island Promoter Hypermethylation Patterns

Meehan, Sproul and co-workers conclude that general aberrant promoter hypermethylation in cancer does not promote tumorigenesis, but instead reinforces transcription repression inherited from pre-cancerous tissue.
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Horizon Launches SyntheTx Partnership Program

H3 Biomedicine is first partner for program aimed at generating ‘first-in-class’ patient-relevant targets based on synthetic lethality screens.
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New de novo Genetic Mutations in Schizophrenia Identified

Columbia University Medical Center (CUMC) researchers have identified dozens of new spontaneous genetic mutations that play a significant role in the development of schizophrenia, adding to the growing list of genetic variants that can contribute to the disease.
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New de novo Genetic Mutations in Schizophrenia Identified

Columbia University Medical Center (CUMC) researchers have identified dozens of new spontaneous genetic mutations that play a significant role in the development of schizophrenia, adding to the growing list of genetic variants that can contribute to the disease.
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Contaminated Site Yields Wealth of Information on Microbes 10 Feet Under

Sequencing of nearly 150,000 genes from soil samples at a former uranium mill site along the Colorado River in Rifle, Colo.
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Researchers Discover Gene That Causes Deafness

University of Cincinnati scientists have found a new genetic mutation responsible for deafness and hearing loss associated with Usher syndrome type 1.
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Cornell Connects Research with the Farmers

Dr. Mazourek brings organic plant breeding to N.Y. growers.
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