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UK Will Offer Genomic Expertise To Find COVID-19 Virus Variants
News   Jan 26, 2021

The UK will offer its world-leading genomics expertise to identify new variants of the virus that causes COVID-19 to countries who do not have the resources to do so.

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Biologists Unravel the Mechanism of Break-Induced Replication
News   Jan 26, 2021

Break-induced replication (BIR) is a way to solve those problems. In humans, it is employed chiefly to repair breaks in DNA that cannot be fixed otherwise. A new study seeks to tease out BIR’s high risk-reward arrangement by describing for the first time the beginning-to-end sequence in BIR.

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Large-Scale Study Identifies Genes That Increase the Risk of Bedwetting
News   Jan 25, 2021

A team of scientists from Aarhus University (AU) and Aarhus University Hospital (AUH) has identified genetic variants that increase the likelihood of nocturnal enuresis (NE) – commonly referred to as bedwetting.

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Promising Immune Response to SARS-CoV-2 Developed by Rhesus Macaques
News   Jan 25, 2021

In a promising result for the success of vaccines against COVID-19, rhesus macaque monkeys infected with the human coronavirus SARS-CoV-2 developed protective immune responses that might be reproduced with a vaccine.

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Scientists Get a Close-Up of the Ribosomal RNA Production Line
News   Jan 25, 2021

Researchers used cryo-electron microscopy (cryo-EM) to capture the structures of RNA polymerase while in complex with DNA and showed how its activity is changed in response to poor-growth conditions.

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Microbiome Search Engine 2 Aids Microbiome Exploration
News   Jan 25, 2021

The importance of microbiomes in health and disease, in humans, animals and the environment, is becoming increasingly clear. Researchers have developed the Microbiome Search Engine 2 (MSE 2) to aid studies by correlating newly developed microbiomes with existing data sets.

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Gene-Editing “Branches Out” With Engineered Variant of CRISPR-Cas9
News   Jan 25, 2021

Introducing SpRY, a newly engineered variant of the famed gene editing tool CRISPR-Cas9. SpRY essentially removes the barriers of what can and can't be targeted for gene editing, making it possible for the first time to target nearly any genomic sequence in plants for potential mutation.

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Genetic Energy Boost Reverses Cellular Effects of Motor Neuron Disease
News   Jan 25, 2021

A study examining the damage caused to nerve cells by motor neuron disease (MND) has shown that by targeting these cells’ energy centers, called mitochondria, neuronal function can be restored.

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Detailed Map of the Skin Points to New Drug Targets for Inflammatory Diseases
News   Jan 22, 2021

Researchers have created a highly-detailed atlas of the skin, which reveals that cellular processes from development are reactivated in cells from patients with inflammatory skin disease. This knowledge will help to identify potential new drug targets for treating skin diseases such as eczema and psoriasis.

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Key to Improving Honey Bee Pathogen Tolerance May Lay With Wild Relatives
News   Jan 22, 2021

Understanding the genetic and environmental factors that enable some feral honey bee colonies to tolerate pathogens and survive the winter in the absence of beekeeping management may help lead to breeding stocks that would enhance survival of managed colonies, according to a recent study.

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