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Tumor "Mutational Signatures" Predict Treatment Response
Researchers have found that so-called “mutational signatures” – that reflect a collection of mutations found across the entire genome of a tumor – can predict the activity of various drugs applied to cancer cells from several tumor types.
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New Theory Looks at How Biodiversity Affects Interspecies Interaction
The term biodiversity invites images of lush rainforests, dynamic estuaries, and other biomes where a kaleidoscope of species interact within their communities. Now a new study has proposed a theory of how biodiversity affects the amount of interspecies interaction in a community.
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A Better Starting Point for Gene-Editing Tools
Most Cas9s are too big to be fitted into popular genome therapy vectors, such as the adenovirus-associated virus (AAV). Cornell scientists provide an explanation for how this problem is solved by nature: they define with atomic precision how a transposon-derived system edits DNA in RNA-guided fashion.
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Seven Healthy Habits Could Lower Risk of Dementia in Those With Genetic Predisposition
Seven healthy habits and lifestyle factors may play a role in lowering the risk of dementia in people with the highest genetic risk, according to research published in the medical journal of the American Academy of Neurology.
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Mystery of the Disappearing T-Cell Genes
According to research, it’s likely that all snakes and lizards are missing one set of T lymphocyte cells.
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Epigenetic Differences Exist Between Different Groups of Type 2 Diabetes Patients
A new study has evidenced the epigenetic differences between groups of type 2 diabetes patients, highlighting the need for personalized treatment strategies.
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Gene Defect That Leads to Autoimmune Disease and Allergy Discovered
A mutation of the IL-33 gene in the human genome that results in multiple allergic disease manifestations and autoimmune disease has been described for the first time.
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Discovery of a New Gene That Drives Heart Muscle Cell Degradation
Researchers have identified a new gene, ZBTB11, that drives heart muscle cell degradation.
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Previously Unknown Mutation Provides New Clues About Epilepsy
A newly identified, single nucleotide mutation to the gene that produces an ion channel protein has provided vital clues into the mechanisms of epilepsy.
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Targeted Next-Generation Sequencing Can Help To Diagnose Primary Immune Deficiency Disorders
Next-generation sequencing can allow affordable testing of multiple genes, enabling earlier and more accurate diagnosis for patients with primary immunodeficiency disorders.
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