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New Method for Generating More Accurate Polygenic Risk Scores
To generate more accurate predictions of disease risk, a research team has used data from more diverse populations to remove the current Eurocentric bias.
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Can Quantum Mechanics Explain Why DNA Spontaneously Mutates?
The molecules of life, DNA, replicate with astounding precision, yet this process is not immune to mistakes and can lead to mutations. Using sophisticated computer modelling, a team of physicists and chemists at the University of Surrey have shown that such errors in copying can arise due to the strange rules of the quantum world.
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Tracing a Cancer's Family Tree To Reveal Key Evolutionary Moments
A lineage-tracing approach has been applied to cancer cells to observe how and when important cancer cell traits evolved.
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Gene Editing Gives Alcohol-Addicted Rat Brains a "Factory Reset"
A study in rats has shown the epigenetic reprogramming associated with binge drinking in adolescence can be reversed with gene editing, potentially offering treatment for alcohol use disorder.
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First Panoramic Spatial Atlases of Life Released
Spatially resolved transcriptomics studies have been used to examine the cellular dynamics of organisms during development, enabling the design of spatial atlases of life.
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Discovery Could Help the Development of Cells To Restore Hearing
Scientists have discovered a "master gene" that programs ear hair cells to be either inner or outer cells, progressing research into recovering hearing loss.
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New Method Fine Tunes Gene Expression by Supplying and Removing Electrons
A new method has been developed to control gene expression with electrical signals, which could help control biomedical implants.
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Cephalopod Genomes Are As “Wonderfully Weird” As the Animals Are
Scientists have dug into the cephalopod genome to understand how these unusual animals came to be. Along the way, they discovered cephalopod genomes are as weird as the animals are.
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The Secret to Herpesvirus Awakening
Dormant herpesviruses induce their reactivation via a previously unknown cellular mechanism mediated by a viral microRNA, a new study has shown.
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Parkinson’s Gene and Vocal Issue Link Could Lead to Earlier Diagnosis
One of the earlier symptoms of Parkinson's is vocal-related issues and a team has identified a Parkinson's-associated gene that may cause them, potentially enabling earlier diagnosis.
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