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Two Drugs Targeting DNA Damage Response Show Promise in Early-Stage Cancer Trials
Early-stage clinical trials of two drugs that target the DNA damage response pathway in cancers have shown that the drugs are safe and clinically beneficial for treating advanced tumors.
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First Strong Genetic Risk Factor for Bipolar Disorder Found
A genetic study of thousands of people with bipolar disorder has enabled researchers to identify that the gene AKAP11 is a strong genetic risk factor for the disorder.
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Immune "Fingerprint" Could Improve Success of Autoimmune Disease Treatments
Most autoimmune diseases are easy to diagnose but hard to treat, but a recent study proposes using your unique immune cell fingerprint to identify rapidly which treatments will work for your autoimmune disease.
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Genetic Influence on Prenatal Response to Air Pollution
Studies on animal models have revealed that a gene affecting immune function and stress response in adults may also play a protective role against particulate pollution during pregnancy.
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Impact of DNA Evidence in Assault Prosecution
In a project funded by the National Institute of Justice, researchers examined the role of DNA evidence in more than 100 sexual assault cases accepted for prosecution in one metropolitan jurisdiction between 2005 and 2010.
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Mutations in Noncoding DNA Protect the Brain From ALS
A mutation in a noncoding DNA gene that affects the brain's immune cells can protect the brain from inflammation, a characteristic symptom of ALS.
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Rain Prompts Plants To Activate Their Immune Systems
A recent study revealed that when plants are exposed to rain, hair-like structures on the leaf surface recognize this rain as a risk factor for causing disease and activate their immune system to prevent infections.
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“Secret Doors” on Human Proteins Could Open Up New Drug Opportunities
The number of potential therapeutic targets on the surfaces of human proteins is much greater than previously thought, according to the findings of a new study in the journal Nature.
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“Landmark” Study Identifies Genome Regions That Influence Schizophrenia Risk
A collection of studies underscore an emerging view of schizophrenia as a breakdown in communication at the synapse, and illustrate how different kinds of genetic variation affecting the same genes can influence risk.
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How Do Milk-Producing Cells Change Over Time in Nursing Mothers?
For the first time, researchers have performed a large-scale, high-resolution study of the cells in breast milk, allowing them to track how these cells change over time in nursing mothers.
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