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Researchers have profiled thousands of individual cells sampled from brain tumors. The findings and methods used represent a significant advance in cancer research, and may lead to better ways of detecting, monitoring and treating cancers.

When many mutations are combined in a cancer cell, new features can emerge. Biologists are using a mathematical approach to find important genetic interactions associated with cancer.

Researchers have discovered a way to use gene therapy to turn glial brain cells into neurons, restoring visual function and offering hope for a way to restore motor function.

Researchers have found that aging produces significant changes in the microbiome of the human small intestine distinct from those caused by medications or illness burden.

New research has identified proteins called linker histones as the factor that controls whether DNA winds into long and thin chromosomes, made up of many small loops, or short and thick chromosomes with fewer large loops.

A nationwide team of researchers has determined how a genetic mutation found in mice and monkeys interferes with viruses such as HIV and Ebola. They say the finding could eventually lead to the development of medical interventions in humans

A growing number of people are suffering from hearing loss due to exposure to loud noises from heavy machinery, concerts, or explosions. As a result, scientists have been working to understand the mechanism behind how the damage to hearing actually occurs.

Researchers at Penn State have created a novel framework that can predict with reasonable accuracy the amino-acid changes in the virus’ spike protein that may improve its binding to human cells and confer increased infectivity to the virus.

According to murine model findings, a single common genetic mutation may hold the key to making immunotherapy more effective against gliomas.

By supplementing the synthetic biology toolkit, researchers have developed key components of an expanded genetic code system.