News

A protein called Oct2 has been identified as the master regulator behind the development of antibody-producing cells. The findings may help understand how certain cancers arise.

Estrogen receptor α (ERα) plays a key role in several breast cancers. New research in Cell reports that in addition to its activity in the nucleus, it can also help cancer cells overcome anticancer mechanisms and develop resistance to treatment.

Scientists have used tools enhanced with AI to successfully propose a new combination of drugs for use against an incurable childhood brain cancer.

Researchers have analyzed a dataset that included more than 31,000 study participants in order to gain significant new insight into the genetic regulation of blood cells.

Researchers have reversed Kleefstra syndrome, a genetic disorder that leads to intellectual disability, in a mouse model of the disease. The series of experiments showed that postnatal treatment resulted in improved symptoms.

More than 50% of patients with ovarian clear cell carcinomas display mutations in the ARID1A gene. Scientists have found that loss of ARID1A function enhances a cellular stress response pathway that promotes survival of cancer cells, which become sensitive to pharmacological inhibition of this pathway.

Proteins in the brain called prions are well known for their involvement in causing disease, but a study has suggested they may help yeast cope with rapidly changing environmental conditions.

Researchers have used statistical mechanics to explore the phenomenon of so-called expression waves of gene regulation.

Researchers have discovered a bacterial enzyme that could make it easy to cut and edit RNA with the kind of precision that, until now, has only been available for DNA editing.

People infected with the original strain of SARS-CoV-2 early in the pandemic produced a consistent antibody response, making two main groups of antibodies to bind to the spike protein. However, a new study has found that those antibodies don’t bind well to newer variants.