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Exploring the Origins of Lung Cancer in Never Smokers
Research published in Nature Genetics shows that in lung cancer patients with no history of smoking, the majority of tumors arise from the accumulation of mutations caused by natural processes in the body
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Synthetic Exosomes Can Optimize Wound Healing
Scientists have engineered synthetic exosomes that regulate cellular signaling during wound closure. The synthetic structures are built to resemble naturally occurring extracellular vesicles that play a fundamental role in communication between cells during various processes in our body.
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Human Melanocyte “Atlas” Could Help To Design Targeted Melanoma Treatments
Researchers have generated the first “atlas” of human melanocytes. In analyzing the atlas data, it was discovered that there are different types of melanocytes and researchers predict these discoveries will lead to more targeted treatments for melanoma.
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Plant Bulbs a Mixing Pot for Drug-Resistant Pathogens
Researchers from Japan have discovered that fungicide-resistant strains of a potentially lethal pathogen have been hiding among plant bulbs.
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Intricacies of Flatworm Regeneration Revealed
The free-living planarian Schmidtea mediterranea is capable of regenerating an entire body from a tiny portion of tissue. How it accomplishes this has largely been a mystery. In a recent study, researchers show that whole-body regeneration involves transcriptional changes in cells from all three germ layers of the body, and that tissue from areas distant from, as well as nearby to the site of injury, contribute to the process of regeneration.
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In the Absence of DNA, Did Heat Cause the First Cells To Divide?
Without genetic material, how did the earliest cells divide? A new theoretical model suggests that heat might have been the driving force. The study is published in Biophysical Journal.
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Genetic Defect in IBD Patients Linked to Gut Leakiness
A team of researchers led by a biomedical scientist at the University of California, Riverside, has identified a novel mechanism by which loss-of-function mutations in the gene PTPN2, found in many patients with inflammatory bowel disease, or IBD, affect how intestinal epithelial cells maintain a barrier.
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Antibiotic Resistant Salmonella Enteritidis From Poultry Could Infect Humans
Researchers sequenced the genome of a virulent Salmonella serovar Enteritidis strain that sickened two poultry flocks in consecutive years and found that it was both antibiotic resistant and could potentially infect humans. Characterizing the strain will aid public health agencies in tracing outbreaks and preventing exposures.
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Getting to the Core of Better Apples
A new platform housing data from over 100 apple varieties could shave years off of the breeding process and enable data-driven assessments of how to boost the health benefits of America’s favorite fruit.
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Gene Mutation Helps Tumors To Evade Immune Detection
Researchers have discovered a novel mechanism showing how a certain gene mutation allows tumors to evade detection by the immune system in colorectal cancer patients.
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