News

Researchers carried out gastric cancer circRNA profiling and identified circURI1 as having higher expression in gastric cancer compared to healthy tissues. They also discovered that circURI1 inhibited cell migration and invasion in vitro and gastric cancer metastasis in vivo.

A CRISPR screening tool has been used to identify a new therapeutic target to treat acute myeloid leukemia (AML) that may have fewer side effects than current approaches.

A collaborative team of researchers, including CRISPR pioneer Feng Zhang, have developed a novel system known as SEND that harnesses human proteins to deliver molecular therapies.

Archaeogenetics has provided an understanding of how the movement and admixture of people across Europe shaped genetic ancestries. However, not all regions are equally represented. Researchers have now sequenced whole genomes of 28 individuals from present-day eastern Croatia and gained new insights into the region’s genetic history and social structures.

Differences in impulsivity between individuals are linked to both experience and gene expression, according to a study on the ancestor of domestic chickens, the red junglefowl.

Microorganisms have persisted below the seafloor for millions of years under extreme energy limitations and continue to evolve.

A new genome-wide association study pinpoints new target genes, cell types and mechanisms for treating chronic kidney disease.

Researchers have conducted a comparison of the genomes of multiple strains of the cacao tree to provide insights into the role of genomic structural variants in the regulation of gene expression and chromosome evolution.

When agricultural weeds evolve resistance to herbicides, they do it either by target-site resistance, a mutation that prevents the chemical from fitting in the protein, or non-target-site resistance, the plant deploys enzymes to detoxify the chemical. Researchers have identified gene regions responsible for non-target-site herbicide resistance in waterhemp.

A gene called PfAP2-HS allows the malaria parasite to defend itself from adverse conditions in the host, including febrile temperatures, according to a new study.