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Scientists have identified a set of human genes that fight SARS-CoV-2 infection. Knowing which genes help control viral infection can greatly assist researchers’ understanding of factors that affect disease severity and also suggest possible therapeutic options.

Researchers have shown that the 'Expansion Hunter' method can detect errors in the DNA that lead to repeat expansion diseases, such as the movement disorder ataxia.

Researchers have made a breakthrough in understanding the role played by high-risk immune genes associated with the development of rheumatoid arthritis.

Using a new single-cell technique, WEHI researchers have uncovered a way to understand the programming behind how stem cells make particular cell types.

Researchers have shown the fundamental role of the heterochromatin protein 1a (HP1a) in the reorganization of the 3D chromatin structure after fertilization. By combining powerful Drosophila genetics with 3D genome modeling, they discovered that HP1a is required to establish a proper chromatin 3D structure at multiple hierarchical levels during early embryonic development.

An article published in the journal EBiomedicine by the group of Dr. Manel Esteller, Director of the Josep Carreras Leukaemia Research Institute and Dr. Aurora Pujol, head of the Neurometabolic Diseases Group of the Bellvitge Biomedical Research Institute (IDIBELL), shows that the epigenetic endowment of each person influences the severity of the COVID-19 disease.

Researchers published an in-depth look at the SARS-CoV-2 mutations that have taken place during the past year in the Journal of General Virology.

A research team has identified and characterized a set of specific super-enhancers that stimulate the activity of related critical cancer genes. The research has also discovered that the deletion of certain specific super-enhancers can reduce tumor cell growth.

Researchers have exploited cryogenic electron microscopy to visualize mechanisms behind DNA damage, by illuminating the mysterious cycle of DNA breakage sensing and repair.

Researchers say the domestic pig is ideal for studies on neonatal brain development and nutrition because their brain size, rate of development, and digestive system are excellent analogs for human newborns.