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Genetic Engineering Explores How Cell Fate Is Determined in the Head
Mammalian embryonic development is an extremely complex and precise process. Researchers have shown how the gene Dlx5 helps direct the generation of tissues in the head.
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DNA Chemical Modifications in Children Conceived by IVF Not Seen in Early Childhood
Compared to newborns conceived traditionally, newborns conceived through in vitro fertilization (IVF) are more likely to have certain chemical modifications to their DNA, according to a study by researchers at the National Institutes of Health.
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Potential Drug Candidates for Difficult-To-Treat Pediatric Leukemia
Scientists have shown that two existing drug candidates hold potential as treatments for a deadly acute myeloid leukemia (AML) subtype that is more common in children.
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Plant Microbiomes Important for Healthy Crops
Two independent studies on apples and pumpkins highlight the importance of the microbiome for health issues from crops to humans.
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Baby's Response to Infectious Disease Impacted by Mother's Fat Intake
Researchers have determined that the type of fats a mother consumes while breastfeeding can have long-term implications on her infant's gut health.
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Molecular Signatures of the Aging Process in Mice Revealed
Researchers have identified aging process molecular signatures in mice. Their analyses provide one of the most comprehensive characterizations of the molecular signatures of aging across diverse types of cells from different tissues in a mammal.
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Targeting the Tumor Environment in Pregnancy-Associated Breast Cancer
A new study has uncovered how breast cancer cells that develop during or after pregnancy alter their environment to allow the formation of more aggressive tumors.
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Editing a Mosquito’s Gut Genes To Make Them Spread Antimalarial Genes
Altering a mosquito’s gut genes to make them spread antimalarial genes to the next generation of their species shows promise as an approach to curb malaria, suggests a preliminary study published today in eLife.
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Intestinal Organoids Show How SARS-CoV-2 Affects the Gut
BU researchers have created human induced pluripotent stem cell-derived intestinal organoids that can be infected with SARS-CoV-2.
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Probiotic Yeast Engineered To Produce Beta-Carotene
In order to produce beta-carotene in the guts of laboratory mice, researchers have genetically engineered a probiotic yeast. The advance demonstrates the utility of work the researchers have done to detail how a suite of genetic engineering tools can be used to modify the yeast.
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