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LRRN4CL Plays a Role in Metastasis of Cancers to the Lungs
A gene not previously linked to cancer has been shown to play a role in the spread of certain cancers to the lungs. When LRRN4CL was overexpressed in mice, melanoma was more likely to metastasize to the lungs.
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Genetic Variant Puts Some Younger Men at Risk of Severe COVID-19
A new study of men with COVID-19 has allowed for the discovery of a genetic variant linked to disease severity. This could mean that men with severe disease may be genetically screened to identify who has the variant and may benefit from interferon treatment.
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Parkinson’s Gene Important for the Generation of Neurons Throughout Life
A gene defect linked to Parkinson’s disease may not only cause the early death of neurons, but also impair the process that generates neurons in the brain throughout our lifetime, a new study has revealed.
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Saliva Test Can Accurately Diagnose Concussion, Rugby Study Shows
A University of Birmingham-led study of top-flight UK rugby players has identified a method of accurately diagnosing concussion using saliva, paving the way for the first non-invasive clinical test for concussion for use in sport and other settings.
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What Can Early-Budding Trees Tell Us About Genetics and Climate Change?
Understanding bud-break genetics enables scientists to modify or select crop varieties more resilient to threats such as climate change.
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Immune Response Insights Obtained With 3D Imaging
Researchers have imaged intact lymphoid organs in three dimensions, and have been able to identify specialized niches, which can determine how immune T cells function. The research is a step forward in understanding the differentiation of T cells and how we can use these crucial findings to inform and optimize vaccine strategies.
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The Secret to Precisely Turning Genes On and Off
In a recent study, scientists have shown how to simultaneously harness multiple forms of regulation in living cells to strictly control gene expression and open new avenues for improved biotechnologies.
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First Full Reference Genome Created for Rye
As one of the founding members of the International Rye Genome Sequencing Group (IRGSG), the University of Maryland (UMD) co-published the first full reference genome sequence for rye in Nature Genetics.
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How Inflammation Leads to Bone Erosion
In a study investigating the mechanism that exacerbates rheumatoid arthritis in smokers, researchers have discovered a novel path in the inflammatory process associated with the bone damage caused by rheumatoid arthritis. The discovery opens up opportunities for new therapeutic interventions for the disease.
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Programming CAR T Cells so That They Only Kill Cancer Cells
A study recently published in the Science journal has found a solution to applying CAR T cell therapy to solid tumours: programming CAR T cells so that they only kill cancer cells, leaving alone healthy cells that have the same marker protein as cancer cells.
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