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TPLATE Protein Complex’s Molecular Architecture Revealed
A recent discovery showed that plants heavily rely on a protein complex named the TPLATE complex for vesicle trafficking. In a new study, VIB teams reveal TPLATE's molecular architecture for the very first time.
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Genes Increase Risk of Obesity but Also Protect Against Disease
Genes have been identified that are linked to both higher levels of body fat and protection from some negative health Impacts caused by obesity.
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Neanderthal Protein May Reduce the Severity of COVID-19
Researchers at the Lady Davis Institute (LDI) at the Jewish General Hospital have discovered that increased levels of the protein OAS1 are associated with reduced mortality and less severe disease requiring ventilation among patients with COVID-19. Using drugs that boost OAS1 levels could be explored to try to improve these outcomes.
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Retroviruses Cause Cancer by Rewriting the Koala Genome
An international team of scientists has shown that a retrovirus invading the koala germline explains the high frequency of koala cancer.
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Not All "Good Cholesterol" Is "Good"
HDL cholesterol has been tagged as "good cholesterol" and associated with a decreased risk of cardiovascular disease. However, research shows that people with large HDL particles actually have an increased risk of myocardial infarction, while only small HDL particles are associated with decreased risk.
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64 Human Genomes Sequenced as a New Reference for Genetic Variation
Researchers have detailed the sequencing of 64 full human genomes. This will enable studies on genetic predispositions to human diseases as well as the discovery of more complex forms of genetic variation.
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Is There a Link Between Depression and Stomach Ulcers?
The conductors of the world's largest study of genetic factors in peptic ulcer disease have said that stomach ulcers are linked to depression.
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Metabolic Pathway for Memory T-Cell Production Mapped
Immunologists have mapped the previously unknown biological machinery by which the immune system generates T cells that kill bacteria, viruses and tumor cells. The findings have multiple implications for how the adaptive immune system responds to infections to generate such memory T cells.
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Cells Responsible for Liver Regeneration Identified
While the amazing regenerative power of the liver has been known since ancient times, the cells responsible for maintaining and replenishing the liver have remained a mystery. Now, researchers have identified the cells responsible for liver maintenance and regeneration while also pinpointing where they reside in the liver.
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A Gene Serves Both a Protective and Destructive Role in Health
Researchers suggest that the gene ENDU-2 could be responsible for triggering tumors in the body. The team discovered that while under stress, ENDU-2 can contribute both to the protection of the organism and to its destruction.
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