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False Positives a Problem for SNP Chips
After hearing of cases where women had surgery scheduled after wrongly being told they had very rare genetic variations in the gene BRCA1 that could significantly increase risk of breast cancer, researchers conducted a large-scale analysis of the technology used. They found that it wrongly identified the presence of very rare genetic variants in the majority of cases.
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Viruses Can Block the Immune Response by Hijacking Cellular Processes
Scientists have found that viruses can "hijack" an existing molecular process in the host cell in order to block the body’s antiviral immune response.
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Antioxidant Found in Green Tea May Increase Levels of p53
p53 is a natural anticancer protein, sometimes called “guardian of the genome” due to its ability to repair DNA damage or destroy cancer cells. A study exploring the interaction between p53 and the green tea compound epigallocatechin gallate now points to a new therapeutic target.
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Experts Discuss SARS-CoV-2 Viral Variants
Scientists from the NIAID outline how SARS-CoV-2 variants have arisen, concerns about whether vaccines currently authorized for use will continue to protect against new variants, and the need for a global approach to fighting SARS-CoV-2 as it spreads and acquires additional mutations.
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Capuchin Monkey Genome Sequenced for the First Time
An international team of scientists has sequenced the genome of a capuchin monkey for the first time, uncovering new genetic clues about the evolution of their long lifespan and large brains.
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What Happens When Our T Cells Are Exhausted?
In chronic infections, the immune system can become exhausted, making it difficult to fight disease. Researchers have looked into how this works.
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How Harmless Gut Bacteria “Turn Bad”
Scientists have determined how harmless E. coli gut bacteria in chickens can easily pick up the genes required to evolve to cause a life-threatening infection. Their study warns that such infections not only affect the poultry industry but could also potentially cross over to infect humans.
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Stressed-Out Mice Pass on Depression-Like Behaviors to Their Offspring via Sperm
In a finding that could reshape our understanding of how mental health disorders arise, Chinese researchers have reported that male mice showing depression-like behaviors were able to pass on those traits to their offspring, apparently through genetic material encoded in their sperm.
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Using Machine Learning To Create Better Gene Therapies
Machine learning study initiated at the Wyss Institute in collaboration with Google Research enables unprecedented AAV capsid diversification with potential for improving gene therapies.
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Suitcase Lab Enables Rapid, Portable SARS-CoV-2 Testing
The small, mobile laboratory could provide rapid coronavirus test results in regions of Africa where testing facilities and medical infrastructure fall far short of European standards.
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