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“Rewiring” at Non-Coding Genome Regions Important for Adaptation content piece image
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“Rewiring” at Non-Coding Genome Regions Important for Adaptation

Scientists shows that ‘genetic rewiring’ at non-coding regions - rather than mutations to protein-coding regions of genes - may play an important role in how cichlid fish are able to rapidly adapt to fill a staggeringly wide range of environmental niches in the East African Rift lakes.
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Structure of Plants’ Energy Generators Revealed

Researchers have revealed the first atomic structures of the respiratory apparatus that plants use to generate energy. The 3D structures of these large protein assemblies – the first described for any plant species – are a step towards being able to develop improved herbicides that target plant respiration.
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Gene Variant Identified as Stroke Risk Factor in Elderly Patients

A team of Geisinger researchers has identified a common genetic variant as a risk factor for stroke, especially in patients older than 65.
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A Multipronged Attack Can Halt Multi-Resistant Bacteria in Their Tracks

Infectious diseases caused by bacteria may be treated with antibiotics. But sometimes, the bacterium becomes resistant to the treatment which results in a long and complicated course of disease. Recent studies have shown that combining several types of antibiotics can effectively prevent resistance.
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Simulating Evolution To Understand Phenotypic Switching

Using computer simulations built on reasonable assumptions and conducted under careful control, computational bioscientists can mimic real biological conditions. Starting with the original founding population (ancient phase), they can evolve the population over several thousand generations to develop an intermediate phase, and then evolve that generation another several thousand generations to develop a derived phase.
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Computational Tool Differentiates Between Data From Cancer Cells and Normal Cells

Researchers have created a new computational technique to accurately differentiate between single-cell RNA-sequencing data from cancer cells and the variety of normal cells found within tumor samples.
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Lungfish Genome Reveals How Aquatic Vertebrates Conquered Land

A team of scientists has broken a new record for sequencing the largest animal genome to date – the Australian lungfish, one of the few living relatives of the first land vertebrates.
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Rapid Blood Test Identifies COVID-19 Patients at High Risk of Severe Disease

Scientists have shown that a relatively simple and rapid blood test that measures levels of mitochondrial DNA can predict which patients with COVID-19 are at highest risk of severe complications or death.
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Tracking AAV Gene Transfer Vector Biodistribution

The biodistribution of adeno-associated virus (AAV) gene transfer vectors can be measured in nonhuman primates using a new method. The method quantifies whole-body and organ-specific AAV capsids from 1 to 72 hours after administration.
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Videos Illuminate RNA’s Mysterious Folding Process

A new Northwestern University-led study is unfolding the mystery of how RNA molecules fold themselves to fit inside cells and perform specific functions.
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