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Epigenetic Biomarker in Father’s Sperm Linked to Autism
In a study published in the journal Clinical Epigenetics, researchers identified a set of genomic features, called DNA methylation regions, in sperm samples from men who were known to have autistic children.
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This Is How Gene Mutations Lead to Kabuki Syndrome
Scientists have known for years that mutations in the MLL4 gene can cause Kabuki syndrome, a rare developmental disorder. But a new study illuminates new details regarding how this occurs.
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Study Finds Shortened Telomeres in Patients With Severe COVID-19
Patients with severe COVID-19 disease have significantly shorter telomeres, according to a study conducted by researchers at the Spanish National Cancer Research Centre (CNIO) in collaboration with the COVID-IFEMA Field Hospital, published in the journal Aging.
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Surprising Behavior of T Cells Could Explain Some Bone Loss
In diseases characterized by bone loss—such as periodontitis, rheumatoid arthritis, and osteoporosis—there is a lot that scientists still don’t understand. But a recent study describes unexpected behavior of T cells that unlocks a piece of the puzzle.
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Inhibiting Glutamine Metabolism Could Be an Effective Therapeutic Strategy for ARID1A-Mutant Ovarian Cancer
According to a new study, mutations that inactivate the ARID1A gene in ovarian cancer increase utilization of the glutamine amino acid making cancer cells dependent on glutamine metabolism. The researchers also demonstrated that pharmacologic inhibition of glutamine metabolism could be an effective strategy for treating ARID1A-mutant ovarian cancer.
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Kombucha Inspires Creation of a Microbial “Living Material”
Scientists have created a “living material” made from microbes that can respond to stimuli from their surrounding environment. It is hoped the material could find diverse applications in contaminant detection, highlighting damage, for example, to packaging, delivering nutrients or therapeutics and even in creating living photographs.
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These Are the Brain Cells Most Vulnerable to Alzheimer’s Disease
Researchers have identified a molecular signature that links together different cell populations in the brain that are selectively vulnerable to the neurodegenerative condition Alzheimer’s disease (AD).
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Beyond the Brain: How "Noncognitive" Skills Contribute to Educational Attainment
Noncognitive skills and cognitive abilities are both important contributors to educational attainment – the number of years of formal schooling that a person completes – and lead to success across the life course, according to a new study.“
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Researchers Paint the Mind of a Worm Using Fluorescent Technique
Scientists have engineered a coloring technique, known as NeuroPAL (a Neuronal Polychromatic Atlas of Landmarks), which makes it possible to identify every single neuron in the mind of a worm.
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A How To Guide for Creating DNA Origami
Researchers at the National Institute of Standards and Technology (NIST), who have studied DNA origami for years, have compiled the first detailed tutorial on the technique. Their comprehensive report provides a step-by-step guide to designing DNA origami nanostructures, using state-of-the-art tools.
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