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Network of Genes Involved in Congenital Heart Disease Identified
Over two million babies, children, and adults in the United States are living with congenital heart disease--a range of birth defects affecting the heart's structure or function. Now, researchers at Gladstone Institutes and UC San Francisco (UCSF) have made inroads into understanding how a broad network of genes and proteins go awry in a subset of congenital heart diseases.
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Using More Genomic Data Increases Accuracy of Breast Cancer Risk Assessment
A new study investigated two genes associated with breast cancer development in women, and found that mutations of these vary on other risk factors in the human genome.
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Study Shows No Increased Frequency of Cancer-Causing Mutations in Naïve Pluripotent Stem Cells
Pioneering new research has made a pivotal breakthrough that dispels concerns that human stem cells could contain cancer-causing mutations.
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Why “Lab-Made” Proteins Have Unusually High Temperature Stability
Scientists have discovered why proteins developed from the start are more resilient to denaturation than those found in the environment.
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Using Genetics To Guide COVID-19 Treatment
Researchers have discovered two genes involved in the molecular processes of antiviral immunity and inflammation within the lungs.
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Towards Easier Genome Editing
Researchers from Skoltech and their colleagues from Russia and the US have described two new, compact Cas9 nucleases, the cutting components of CRISPR-Cas systems, that will potentially expand the Cas9 toolbox for genome editing.
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Active Enzyme Required To Unlock Carrots' Full Benefit
Carrots are a good source of beta-carotene, which is a precursor of vitamin A. But to get the full health benefits of this superfood, you need an active enzyme to produce this vitamin.
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Role for tRNA in Inflammatory Reaction Following Stroke
tRNA fragments have been shown to play a role in the inflammatory reaction triggered by the immune system following an ischemic stroke. The aim of the research is to find new target structures for therapeutics.
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Muscle Cell Secrets Unlocked
A muscle fiber consists of just one cell, but many nuclei. A team at the MDC has now shown just how varied these nuclei are.
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Diagnostic Marker May Help Predict Response to Cervical Cancer Treatment
A new diagnostic marker has been discovered by scientists that can predict the response to therapeutic treatments of patients with cervical cancer.
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