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Diet-Induced Hepatocyte Regeneration Enhances CRISPR-Mediated Gene Repair
Use of thyroid hormone to boost hepatocyte proliferation enhanced the efficiency of CRISPR/Cas9-mediated gene correction in the mouse liver. This may be a strategy to enhance gene repair within the liver, according to a new study.
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CRISPR Study Identifies Two Genes That Regulate Social Dominance
Scientists have discovered that two paralogous androgen receptor genes control social status in African cichlid fish. The finding may have applications to other species.
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Enzyme That Suppresses the Immune Response to Viral Infections Identified
Scientists have discovered how an enzyme that regulates several cellular processes might be a key target to preventing viruses from disarming the human immune response.
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2 Million-Year-Old Skull From Our Ancient Cousins Found
Following the excavation, reconstruction and analysis of the rare, male fossil in South Africa, Paranthropus robustus was identified as a large-toothed, small-brained hominin that co-existed with our early direct human ancestors as a "cousin species". Researchers argue that this provides the first high resolution evidence for microevolution within an early hominin species.
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Rapid Test Can ID Unknown Causes of Infections Throughout the Body
UCSF scientists have developed a single clinical laboratory test capable of zeroing in on the microbial miscreant afflicting patients hospitalized with serious infections in as little as six hours -- irrespective of what body fluid is sampled, the type or species of infectious agent, or whether physicians start out with any clue as to what the culprit may be.
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Scientists Make Progress in Understanding Immunological Aging
A genetic disposition that plays a role in the development of the heart in the embryo also appears to play a key role in the human immune system is shown by a recent study led by the University of Bonn.
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Vitamin D, Genetics and Preeclampsia
A team of researchers found that the expression of a set of genes previously studied in the setting of early-onset and severe preeclampsia is significantly affected by vitamin D status during late-stage pregnancy.
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Protein Involved In Formation and Maintenance of Bacterial Shield Discovered
Scientists reviewed studies of three essential membrane proteins that monitor not only LPS biosynthesis inside the cell, but also transport to, and proper assembly at the cell surface.
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How Cell Processes Round Up and Dump Damaged Proteins
Scientists at the University of Massachusetts Amherst report that they have discovered how the UCH37 enzyme regulates a cell's waste management system.
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