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Genetics and AI Solve Leonardo da Vinci’s Biological Enigma
Researchers have investigated the function of a complex mesh of muscle fibres that line the inner surface of the heart. The study, published in the journal Nature, sheds light on questions asked by Leonardo da Vinci 500 years ago, and shows how the shape of these muscles impacts heart performance and heart failure.
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New Breast Cancer Database Could Help To Develop Personalized Treatments
A new database of 40 breast cancer cell lines aims to help researchers deepen their understanding of these cell lines and speed up the development of new gene-targeted therapies.
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Insights on Rich Microbial Communities Around Shipwrecks May Aid Conservation Efforts
Researchers have found distinct differences in the composition of microbial communities on and around a shipwreck, suggesting niche partitioning based on biotic and abiotic conditions.
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Protein Influences Regeneration of Vascular Cells
Researchers have discovered how the communication between individual cells can be influenced with the help of a specific protein, which could have implications for the treatment of heart diseases.
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New Insights Into How Skin Can Regenerate After Severe Burns or Injuries
New research has made an exciting leap forward in understanding how skin heals, which could lead to drug treatments to vastly improve wound healing.
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Optogenetic Neuronal Silencing Gets an Upgrade
Scientists have produced mutant variants of a membrane protein that can effectively silence neurons when illuminated.
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A Single Gene Drives Aggression in Wild Songbird
A new study has shown how differentiation of a single gene can change the display of aggressive behavior in the white-throated sparrow.
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Gene Therapy Eliminates Over 90% of Latent Herpes Virus in Animal Model
In Nature Communications, Fred Hutch scientists demonstrate in a mouse model how gene therapy could cure an infection that afflicts billions of people.
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Aging Heart Cells Offer Clues to Susceptibility of Older People to Severe COVID-19
Genes that play an important role in allowing SARS-CoV-2 to invade heart cells become more active with age, according to research published in the Journal of Molecular and Cellular Cardiology.
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Why Younger Female Patients Have Low Response Rates to Some Cancer Immunotherapies
A new study suggests that since the typically robust immune systems of young, female patients are better at getting rid of cancer cells, the cells left behind are not as readily visible to the immune system to begin with, meaning some types of immunotherapy are ineffective.
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