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"Floppy" Proteins Used To Create Artificial Organelles Within Human Cells

Biomedical engineers have developed a method for controlling the phase separation of an emerging class of proteins to create artificial membrane-less organelles within human cells.
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Accelerating Progress in Preventing Resistance to Anticancer Drugs

Researchers have developed new models to study the molecular characteristics of lung and pancreatic tumors that are driven by mutations in the NTRK1 gene.
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Embryos Could Be Susceptible to Coronavirus, Study Suggests

Genes that are thought to play a role in how the SARS-CoV-2 virus infects our cells have been found to be active in embryos as early as during the second week of pregnancy, say scientists at the University of Cambridge and the California Institute of Technology. The researchers say this could mean embryos are susceptible to COVID-19 if the mother gets sick, potentially affecting the chances of a successful pregnancy.
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How Cell Diversity Emerges

A research team at the Max Planck Institute for Molecular Genetics in Berlin has explored the role of factors in embryonic development that do not alter the sequence of DNA, but only epigenetically modify its “packaging”. They describe how regulatory mechanisms contribute to the formation of different tissues and organs in early mouse embryos.
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Blood Test Could Diagnose Baby Brain Damage Just Hours After Birth

A newly developed blood test could detect which babies deprived of oxygen at birth are at risk of serious neurodisabilities like cerebral palsy and epilepsy.
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Inbreeding Detrimental for Survival in Birds

Biologists have long known that inbreeding can be detrimental. Inbreeding results in less genetic variation, making species more vulnerable if changes occur that require them to adapt. Now we know more about just how bad inbreeding really is.
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FMR1 Premutation Carriers Show Brain Connectivity Reductions

A new paper reveals a possible early indicator of Fragile X-associated tremor/ataxia syndrome, or FXTAS. The disease afflicts some older people who carry a "premutation" of the gene known as FMR1, which can lead to impairments in movement and cognition -- while other people who carry the premutation are unaffected.
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Circulating DNA From Tumor Could Predict Immunotherapy Outcome

A newly developed test that detects changing levels of tumor fragments in the blood may be an easy, non-invasive and quick way to predict who will benefit from immunotherapy, according to researchers.
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Gene Variants Help Explain Why People of African Descent Have Far Higher Stroke Risk

African-Americans have up to three times the risk of dying from strokes as people of European descent, yet there has been little investigation of if and how genetic variants contribute to their elevated stroke risk. Until now.
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Machine Learning Method Predicts Cell Fate

Scientists have created a machine learning method and open source software to estimate the dynamics of gene activity in single cells, allowing biologists to robustly predict the future state of individual cells.
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