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Transcriptomic Map of Cerebellum Development Provides Unprecedented Insight
Transcriptomic Map of Cerebellum Development Provides Unprecedented Insight
News   Sep 14, 2018

Researchers have created a massive database of the changes in gene activity of individual cells in the cerebellum during embryonic development and immediately after birth.

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NIH Targets Genetic Cure for Sickle Cell Disease
NIH Targets Genetic Cure for Sickle Cell Disease
News   Sep 14, 2018

The National Institutes of Health announced the launch of a new initiative to help speed the development of cures for sickle cell disease. The Cure Sickle Cell Initiative will take advantage of the latest genetic discoveries and technological advances to move the most promising genetic-based curative therapies safely into clinical trials within five to 10 years.

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New Approach Improves Detection of Diseases at Birth
New Approach Improves Detection of Diseases at Birth
News   Sep 14, 2018

Combining metabolic and DNA testing approaches is a way forward for newborn screening, false positives reduced by half.

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Gut Bacteria’s Shocking Secret
Gut Bacteria’s Shocking Secret
News   Sep 13, 2018

While bacteria that produce electricity have been found in exotic environments like mines and the bottoms of lakes, scientists have missed a source closer to home: the human gut.

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The Sex Life of Strawberries
The Sex Life of Strawberries
News   Sep 13, 2018

The transfer of gene cassettes across generations of strawberry plants has been shown to drive changes in sex chromosomes, according to a team led by a researcher from the University of Pittsburgh Department of Biological Sciences.

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Changes in Mitochondrial DNA Control Severity of Heart Disease
Changes in Mitochondrial DNA Control Severity of Heart Disease
News   Sep 12, 2018

Differences in the DNA within the mitochondria, the energy-producing structures within cells, can determine the severity and progression of heart disease caused by a nuclear DNA mutation. A new study found that when a nuclear DNA (nDNA) mutation was combined with different mild variants of mitochondrial (mtDNA) in mice, the severity of heart disease was markedly different.

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Finding Nemo’s Genes
Finding Nemo’s Genes
News   Sep 12, 2018

In a new study, researchers used high-tech sequencing tools to create one of the most complete genetic maps for the orange clownfish, a common reef inhabitant and star of the Disney movie, Finding Nemo.

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Researchers Claim Discovery of a Long-Distance Running Gene
Researchers Claim Discovery of a Long-Distance Running Gene
News   Sep 12, 2018

In a new paper researchers report on studies of mice engineered to lack a gene called CMAH, and resulting data that suggest the lost gene may have contributed to humanity’s well-documented claim to be among the best long-distance runners in the animal kingdom.

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RNA Silencing Protein Blocked in Liver to Prevent Obesity and Diabetes in Mice
RNA Silencing Protein Blocked in Liver to Prevent Obesity and Diabetes in Mice
News   Sep 12, 2018

Obesity and its related ailments like type 2 diabetes and fatty liver disease pose a major global health burden, but researchers suggest in Nature Communications that blocking an RNA-silencing protein in the livers of mice keeps the animals from getting fat and diabetic conditions.

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Investigating the Birth of a Gene
Investigating the Birth of a Gene
News   Sep 12, 2018

Only very recently were there serious indications that novel protein coding genes might indeed be formed de novo from so-called non-coding DNA, i.e. in parts of the genome that do not produce proteins. Now, for the first time, a new study has examined the earliest stages in the emergence of these de novo genes.

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