Bioethics Council Rules Heritable Genome Editing "Ethically Acceptable" In Certain CircumstancesNews
A leading UK bioethics advisory body has weighed in on the debate around human genetic modification, concluding that heritable genome editing – modifying the DNA of an egg, sperm or embryo with changes that will be passed on to future generations – could be ‘morally permissible’ in humans, provided key ethical tests are met.
Hay Fever Risk Genes Overlap with Autoimmune DiseaseNews
In a large international study involving almost 900,000 participants, researchers from the University of Copenhagen and COPSAC have found new risk genes for hay fever. It is the largest genetic study so far on this type of allergy, which affects millions of people around the world.READ MORE
ExPecto Patronum! Magical Machine Learning Tool Summons DNA Dark Matter DataNews
A new machine learning framework, dubbed ExPecto, can predict the effects of mutations in the so-called “dark matter” regions of the human genome. ExPecto pinpoints how mutations can disrupt the way genes turn on and off throughout your body.
CRISPR Causes More Genome Damage Than First ThoughtNews
Researchers have discovered that CRISPR/Cas9 gene editing can cause greater genetic damage in cells than was previously thought. These results create safety implications for gene therapies using CRISPR/Cas9 in the future as the unexpected damage could lead to dangerous changes in some cells.
Persistent organic pollutants skulk around the environment threatening human health through direct contact, inhalation, and most commonly, eating contaminated food. Now new research suggests it might be just as important to pay attention to the origin of your food’s food.READ MORE
The co-evolution of plant - pathogen interactions has been revealed in unprecedented detail in a study of one of the world’s deadliest crop killers. This is the rice blast pathogen, which destroys enough food to feed more than 60 million people every year – almost the population of the UK.
Exposure to cold prior to conception causes the resulting offspring to have more brown adipose tissue, which protects against excess weight and metabolic disorders. Scientists studying mice have discovered that this information is passed on by the sperm, and there is a similar correlation in humans.READ MORE
Scientists have discovered that it is possible to identify people at high risk of developing acute myeloid leukaemia (AML) years before diagnosis.READ MORE
Researchers have for the first time used a gene editing technique to successfully cure a genetic condition in a mouse model. Their findings, published in Nature Communications, present a promising new avenue for research into treating genetic conditions during fetal development.
Researchers have uncovered a key function of ATR, a protein in charge of responding to DNA damage during the formation process of sperm precursor cells. They also showed that inhibiting ATR caused issues that block sperm formation.READ MORE
UC San Francisco researchers have identified the sequence of genetic changes that transform benign moles to into malignant skin cancer and have used CRISPR gene editing to recreate the steps of melanoma evolution one by one in normal human skin cells in the lab.READ MORE
Researchers have developed a chip that can detect a type of genetic mutation known as a single nucleotide polymorphism (SNP) and wirelessly send the results in real time to a smartphone, computer, or other electronic device. The chip is at least 1,000 times more sensitive at detecting an SNP than current technology.
With this new site, the company will be able to respond to the growing global demand for foot-and-mouth disease and Bluetongue virus control.READ MORE