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Insights into Asian Ancestry and Genetic Diversity
After a global genetic comparison, scientists have discovered that Asia has at least ten ancestral lineages, whereas northern Europe has a single ancestral lineage.
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Worms Reveal Critical Step in Insulin Synthesis
The identification of a protein important for insulin synthesis may hold clues for understanding the pathogenesis of diabetes.
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Reward Circuit Protein Could Influence Addiction, Suggests Mouse Study
The reward pathway of the brain causes feelings of happiness but is also involved in behavioral disorders like schizophrenia and addiction. A breakthrough study by scientists in Japan has now identified the role of a protein called Npas4 in the reward pathway, mediated by the well-known proteins MAPK and CBP, opening doors to potential therapies for associated disorders.
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A New Treatment For Elephantiasis?
Using RNA sequencing techniques, researchers have discovered that an experimental cancer drug could be used to treat a disabling parasitic disease.
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Exploring the Synthetic Biology Revolution
Cell-free engineering has evolved from a specialized research tool to the backbone of a variety of applications in synthetic biology that stand to dramatically impact society, from the environment to medicine to education.
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A Genetic Network Sheds Light on the Evolution of the Modern Human Face
A study has identified a genetic network involved in the unique evolutionary trajectory of the modern human face and prosociality not found in Neanderthals.
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The Cellular Culprits Behind Alzheimer's Disease
Scientists have developed an online atlas of gene expressions at single-cell level in Alzheimer’s disease brains, aiming to boost to efforts to identify gene targets for drug development.
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Glow-in-the-Dark Cells Expose Mutations Driving Malignancy
Scientists have discovered how stem cell mutations quietly arise and spread throughout a widening field of the colon until they eventually transform into a malignancy.
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Ribosome-based Treatments: A Sought After Therapy Option for Orphan Diseases?
Recently, Urania Therapeutics announced that it has successfully raised €3.53M ($3.89M) in seed funding to unlock the therapeutic potential of ribosome-based treatments. We spoke with Jean-Paul Renaud, President and CSO of Urania Therapeutics, to learn more about the mechanisms of readthrough compounds and how the company hopes to provide treatment solutions for orphan diseases.
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Silencing Retroviruses To Awaken Cell Potential
Researchers led by a team from the University of Tsukuba identify a protein that suppresses retroviruses in the human genome, allowing the reprogramming of somatic cells to unlock their hidden potential.
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