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Thieving Cholera Bacterium Can Steal Up to 150 Genes in One Go
A research group has discovered the extent of DNA that V. cholerae can steal in a single attack: more than 150,000 nucleic acid base pairs, or roughly 150 genes in one go (the cholera bacterium carries around 4,000 genes in total). The researchers calculated this number by sequencing the entire genome of almost 400 V. cholerae strains before and after stealing DNA from their neighboring bacteria.
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Gene Therapy for Duchenne Muscular Dystrophy Safely Preserves Muscle Function
Researchers have successfully halted the effects of Duchenne muscular dystrophy in animal models, using a developing gene therapy.
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One Step Closer to Personalized Crohn's Treatment
A study investigating why some drugs fail some patients with Crohn’s disease has identified a genetic marker that could individualize drug treatment.
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2019 Nobel Prize in Physiology or Medicine Announced
The 2019 Nobel Prize in Physiology or Medicine has been jointly awarded to William G. Kaelin, Jr., Sir Peter J. Ratcliffe and Gregg L. Semenza for their discoveries of “how cells sense and adapt to oxygen availability.”
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Unlocking CRISPR's Potential To Alter the Microbiome
Researchers at Western University have developed a new way to deliver the DNA-editing tool CRISPR-Cas9 into microorganisms in the lab, providing a way to efficiently launch a targeted attack on specific bacteria.
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Urothelial Organoids Could Advance Bladder Cancer Research
CNIO researchers have used organoid technology to establish long-term cultures of normal mouse urothelial cells that maintain their identity, from which they identified a population of proliferating stem cells - important for the origin of bladder cancer- that could not be studied until now.
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First Complete Picture of the Florida Panther Genome
Scientists determined the first complete picture of the Florida panther genome – work that could serve to protect that endangered population and others.
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Soybean Pathogen Genome – Assemble!
An international research collaboration has successfully assembled the complete genome sequence of the pathogen that causes the devastating disease Asian soybean rust.
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The Curious Incident of the Blind Dog in the Night-time
A new study has identified the gene responsible for congenital night blindness in dogs.
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Keeping the Gene Expression of Sex Chromosomes in Balance
Scientists have uncovered a chromosome-wide mechanism that keeps the gene expression of sex chromosomes in balance in our cells. The findings shed light on molecular reasons for early miscarriage and could be important for the emerging field of regenerative medicine.
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