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New Drug Combo Could Work Against Broader Array of Cancer Cells
Researchers have discovered two drugs that work together to disrupt cancer cells’ ability to survive.
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DNA Fracturing Causes Rewiring of Genes in Cancer
A new study has brought attention to genomic structural variation as a previously unappreciated mechanism involved in altering DNA methylation, a form of gene control, in human cancers.
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Revival of 50,000-Year-Old Gene Reveals How Deadliest Malaria Parasite Jumped From Gorillas to Humans
In a study published today in PLOS Biology, researchers from the Wellcome Sanger Institute and the University of Montpellier have reconstructed a ~50,000-year-old gene sequence acquired by the ancestor of Plasmodium falciparum. The acquisition of the gene sequence enabled the parasite to infect human red blood cells.
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Microbiome Is Shaped by Genetic Differences in the Immune System
Genetic differences in the immune system shape the collections of bacteria that colonize the digestive system, according to new research by scientists at the University of Chicago.
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New Genetic-based Epilepsy Risk Scores
Researchers have developed new genetic-based epilepsy risk scores which may lay the foundation for more personalized diagnosis and treatment.
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Mapping the Evolutionary History of Oaks
Researchers have uncovered the 56-million-year evolutionary history of oaks.
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New Genetic Engineering Tool Opens Floodgates of Microbial Metabolite Applications
A team of microbiologists and genomicists led by the Department of Energy Joint Genome Institute (JGI) has invented a genetic engineering tool, called CRAGE, that could not only make studying microbes much easier, but also fill significant gaps in our understanding of how microbes interact with their surroundings and evolve.
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It's Time To Keep Check on the Microbiome
Scientists have developed a novel technique based on an oscillating gene circuit that they hope will help to shed light on the human microbiome.
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Powerful Technique Tracks Down Genetic Disease
A team led by a scientist at Scripps Research has invented a new genomics technique for tracking down the causes of rare genetic diseases. The new method compares activity levels of maternal and paternal alleles across the genome and detects when the activity of an allele lies far enough outside the normal range to be a plausible cause of disease.
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