Bioethics Council Rules Heritable Genome Editing "Ethically Acceptable" In Certain CircumstancesNews
A leading UK bioethics advisory body has weighed in on the debate around human genetic modification, concluding that heritable genome editing – modifying the DNA of an egg, sperm or embryo with changes that will be passed on to future generations – could be ‘morally permissible’ in humans, provided key ethical tests are met.
Hay Fever Risk Genes Overlap with Autoimmune DiseaseNews
In a large international study involving almost 900,000 participants, researchers from the University of Copenhagen and COPSAC have found new risk genes for hay fever. It is the largest genetic study so far on this type of allergy, which affects millions of people around the world.READ MORE
ExPecto Patronum! Magical Machine Learning Tool Summons DNA Dark Matter DataNews
A new machine learning framework, dubbed ExPecto, can predict the effects of mutations in the so-called “dark matter” regions of the human genome. ExPecto pinpoints how mutations can disrupt the way genes turn on and off throughout your body.
CRISPR Causes More Genome Damage Than First ThoughtNews
Researchers have discovered that CRISPR/Cas9 gene editing can cause greater genetic damage in cells than was previously thought. These results create safety implications for gene therapies using CRISPR/Cas9 in the future as the unexpected damage could lead to dangerous changes in some cells.
Scientists have shown that widespread transfer of genes between species has radically changed the genomes of today’s mammals, and been an important driver of evolution. In the world’s largest study of so-called “jumping genes”, the researchers have traced two particular jumping genes across 759 species of plants, animals and fungi.
Scientists report the protein complex mTORC1 serves as a bridge between environmental signals and metabolic programs to influence the fate of developing T cells.READ MORE
The complexity of the human brain presents scientists with immense challenges as they try to find new treatments for a host of diseases and conditions. But the advent of a new technology known as single-cell RNA sequencing is opening a window into how the brain works.
The arrival of Europeans to the Americas, beginning in the 15th century, all but wiped out the dogs that had lived alongside native people on the continent for thousands of years, according to new research.READ MORE
Researchers have discovered that transfer of vital genetic information within a cell isn’t the one-way telegraph once thought, opening new pathways for understanding human disease and developing potential treatments, a new study shows.
EFSA has published two reports which provide a picture of how whole genome sequencing (WGS) can be used in food safety and how extensively such techniques are used in Europe.READ MORE
Locking DNA knots in place thanks to DNA propensity to be supercoiled. A new study by SISSA suggests that is one of the mechanisms that could be harnessed by the cellular machinery to deal with those accidental entanglements that can compromise DNA
An international team of scientists, led by geneticists from Trinity, have sequenced the genomes from ancient goat bones from areas in the Fertile Crescent where goats were first domesticated around 8,500 BC. They reveal a 10,000-year history of local farmer practices featuring genetic exchange both with the wild and among domesticated herds, and selection by early farmers.
A recent study has shown that replacing some rice with less thirsty crops could dramatically reduce water demand in India, while also improving nutrition.READ MORE