DNA Traces Illegal Ivory Shipments Back to Major CartelsNews
The international trade in elephant ivory has been illegal since 1989, yet African elephant numbers continue to decline. A study reports that DNA test results of ivory seizures made by law enforcement have linked multiple ivory shipments to the same network of dealers operating out of a handful of African ports.READ MORE
Cancer cells often have mutations in their DNA that can give scientists clues about how the cancer started or which treatment may be most effective.READ MORE
The effects of KRAS mutations underlying many different types of cancer are more diverse than previously thought, according to a new study. Different mutations in the same amino acid of the KRAS protein have so varied effects on protein function that they may require different approaches when it comes to treatment and drug development.READ MORE
Individualised therapies that target the specific genetic features of tumors have the potential to transform cancer diagnosis, treatment and care. However, several challenges still need to be overcome before these approaches can be widely used in the clinic. Two DNA testing programmes have been implemented in institutes in Spain and the UK, to match patient tumor profiles with targets of early clinical trials, and to embed whole genome sequencing (WGS) in routine oncology practice, respectively.READ MORE
Researchers have discovered how a mutation in a gene regulator called the TERT promoter - the third most common mutation among all human cancers and the most common mutation in the deadly brain cancer glioblastoma - confers "immortality" on tumor cells, enabling the unchecked cell division that powers their aggressive growth.READ MORE
Study connecting RNA stress granules with autophagy provides insights on treatment approaches for degenerative ataxia.READ MORE
Whether an individual develops a neurodevelopmental disorder like autism or ADHD and the severity of that disorder depends on genetic changes beyond a single supposedly disease-causing mutation. A new study reveals that the total amount of rare mutations in a person’s genome can explain why individuals with a disease-associated mutation can have vastly different symptoms.
How and why human-unique characteristics such as highly social behavior, languages and complex culture have evolved is a long-standing question. A research team led by Tohoku University in Japan has revealed the evolution of a gene related to such human-unique psychiatric traits.