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Epigenetic Drug Strategy to Treat Cancer
Epigenetic Drug Strategy to Treat Cancer
News   Oct 26, 2018

Researchers have discovered that inhibiting CDK9, a DNA transcription regulator, reactivates genes that have been epigenetically silenced by cancer.

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Targeted Drug Could Slow Ovarian Cancer Progression in Women with Faulty BRCA Gene
Targeted Drug Could Slow Ovarian Cancer Progression in Women with Faulty BRCA Gene
News   Oct 26, 2018

A drug could help slow the progression of some advanced ovarian cancers and extend the time that patients show no signs of disease, according to new clinical trial results.

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BASF licenses CRISPR-Cpf1 from the Broad Institute of MIT and Harvard
BASF licenses CRISPR-Cpf1 from the Broad Institute of MIT and Harvard
News   Oct 26, 2018

The chemical company BASF has attained a global, non-exclusive licensing agreement with the Broad Institute of MIT and Harvard for the use of CRISPR-Cpf1 genome editing technology to improve products in agricultural and industrial microbiology applications.

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Tetracyclines Found in Cellular Hide and Seek
Tetracyclines Found in Cellular Hide and Seek
News   Oct 26, 2018

The intricate quest to discover where tetracyclines go in human cells is over, helping to understand the promising results shown in their use to treat pathological inflammation and cancer.

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Earlham's Aequatus Tool Enables Homologous Gene Comparison
Earlham's Aequatus Tool Enables Homologous Gene Comparison
News   Oct 26, 2018

Aequatus - a new bioinformatics tool developed at Earlham Institute (EI) - is helping to give an in-depth view of syntenic information between different species, providing a system to better identify important, positively-selected, and evolutionarily-conserved regions of DNA.

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Screening Tool Developed to Reduce Inappropriate Antibiotic Use
Screening Tool Developed to Reduce Inappropriate Antibiotic Use
News   Oct 26, 2018

The precision medicine platform is 1,000 times more sensitive than conventional screening methods and can detect signs of antibiotic resistance.

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Summary of All Known Human Genes Involved in Human Cancer
Summary of All Known Human Genes Involved in Human Cancer
News   Oct 25, 2018

Researchers at the Wellcome Sanger Institute have created the first comprehensive summary of all genes known to be involved in human cancer, the "Cancer Gene Census".

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Infant Diet Important for Healthy Gut Long-term
Infant Diet Important for Healthy Gut Long-term
News   Oct 25, 2018

A child has until the age of two-and-a-half to establish healthy gut bacteria – with little change after this point.

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Aged Hippocampal Signalling Pathway Improved in Rodents
Aged Hippocampal Signalling Pathway Improved in Rodents
News   Oct 25, 2018

New details revealed of how a naturally occurring hormone can boost memory in aging mice, laying the groundwork for staving off this form of memory loss in people.

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Normal Function of ALS and Dementia Gene Determined for First Time
Normal Function of ALS and Dementia Gene Determined for First Time
News   Oct 25, 2018

The normal function of a gene associated with the brain diseases amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) has been determined.

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