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Gene Therapy for Niemann-Pick Type a Diseases Moves Forward
Research shows that gene replacement therapy for Niemann-Pick type A disease is safe for use in nonhuman primates and has therapeutic effects in mice.
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Ahead of Million-person Sequencing Program, NIH Funds Genetic Counseling Resource
The All of Us Research Program, part of the National Institutes of Health, has awarded $4.6 million in initial funding to Color, a health technology company in Burlingame, California, to establish the program’s nationwide genetic counseling resource.
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Pluripotency: 'Butterfly Effect' Discovered
Researchers from CNIO have discovered a ‘butterfly effect’, through which a single change at telomeres controls the ability of cells to generate a complete organism.
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The First Precision Medicine Clinical Trial for Dogs With Lung Cancer
A "ground-breaking" new study led by the Translational Genomics Research Institute (TGen) suggests that the HER2 gene that
same gene is the cause of lung cancer in many dogs. Their findings, published in the journal Clinical Cancer Research, offer novel avenues for precision medicine in dogs.
same gene is the cause of lung cancer in many dogs. Their findings, published in the journal Clinical Cancer Research, offer novel avenues for precision medicine in dogs.
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BAFfling Cancer Strategies: New Targets for Chromatin Remodeling Mutations ID'd
Mutations are found in BAF complex genes in approximately every fifth human cancer. Researchers have been using this knowledge to explore ways to target BAF mutant cells.
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Unraveling DNA Methylation Patterns Eases Introduction of Foreign DNA Into Host Cells
DNA methylation is catalyzed by a group of enzymes known as methyltransferases, which strategically decorate DNA with methyl groups in specific patterns. In a new study, scientists have developed a pipeline that allows for the identification of which enzyme causes which specific methylation pattern.
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Drug Screens Identify Potential Lung Cancer Treatment
A team have discovered a potential new treatment approach for lung cancer patients with mutations in the KRAS pathway – a mutation that occurs in approximately 30% of lung cancer patients.
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Children With a High Genetic Risk of Developing Type 1 Diabetes Have Different Gut Microbiomes
According to a new study, genetic risk can shape an individual's response to environmental factors in the development of autoimmune disease.
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Genetic Analysis Gives Insight Into Huntington's Onset
Researchers from the Genetic Modifiers of Huntington’s Disease Consortium have analysed information on more than 9,000 individuals with the disease and found new information about the biological processes underpinning the disease's onset.
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Could Plant Biological Clocks Set the Time for Crop Spraying?
Plant circadian rhythms regulate the sensitivity of plants to a widely used herbicide according to the time of day.The findings could benefit agriculture by reducing crop loss and improving harvests.
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