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Streamlining the Construction Method for Human Artificial Chromosomes
Researchers describe a new way to form an essential part of the artificial chromosome, called the centromere, by bypassing the biological requirements needed to form a natural one.
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Slowing Down the Metabolism May Prevent Harmful Genetic Mutations
Researchers slowed mutant fruit flies' metabolic rates by 50%, and the expected detrimental effects of many mutations never manifested. After experimentally testing fruit flies' many different genetic mutations, the researchers found the same result each time.
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Stem Cell to Neuron... to Be, or Not to Be?
Researchers have unraveled a new mechanism controlling the switch between growth and differentiation of neural stem cells during brain development. A specific factor makes stem cells "deaf" to proliferative signals, causing them to differentiate into neurons and shape the marvelous complexity of our brain.
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Untangling the Genetics Behind Five Psychiatric Disorders
A group of international doctors has uncovered the genes that contribute to the development of ADHD, autism spectrum disorder, bipolar disorder, major depression and schizophrenia.
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First Assessment of Blood Abnormalities in Antarctic Penguin Colony
Scientists have completed the first study of immune and genetic stability among a colony of penguins living in a remote corner of southern Antarctica.
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Looking at "Junk" DNA for Insights Into ASD and Stroke
A new study suggests that by analyzing noncoding mutations, researchers may be able to better understand not only ASD but a variety of conditions, ranging from neurological disorders to heart disease.
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Treatment Takes a "BiTE" Out of Brain Cancer
Investigators have created a new method that could make immune therapy more effective against brain tumors and expand its use against other types of solid tumors.
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Mapping Protein-Gene Interactions in Alzheimer’s Disease
Researchers have used the transcriptome -- the sum of all messenger RNA (mRNA) molecules expressed from genes -- to compare 414 study participants with clinically diagnosed and neuropathologically confirmed AD with an age-matched, non-demented control group from a community-based neuropathological study.
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Understanding Cannflavin Biosynthesis Unlocks Pain Relief Potential of Cannabis
Researchers have discovered how the cannabis plant creates important pain-relieving molecules that are 30 times more powerful at reducing inflammation than Aspirin. The discovery unlocks the potential to create a naturally derived pain treatment.
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Gene Loss 2 Million Years Ago May Explain Why Humans Are Prone to Heart Attacks
Researchers say the loss of a single gene two to three million years ago in our ancestors may have resulted in a heightened risk of cardiovascular disease in all humans as a species, while also setting up a further risk for red meat-eating humans.
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