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Mouse Hallucinations Represent Optogenetic Advance

Hallucinations are spooky and, fortunately, fairly rare. But, a new study suggests, the real question isn't so much why some people occasionally experience them. It's why all of us aren't hallucinating all the time.

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Sex Affects Gene Expression in Mammals

Men are from Mars and women are from Venus, so the saying goes. The differences between the sexes have been explored across a variety of disciplines over many years: philosophy, literature and, of course, science. From a biological perspective, however, the effect that sex has on gene expression, particularly in autosomal (sex-linked) genes, has been a relatively unmapped area – until now.
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Out of Africa and Into an Archaic Human Mixing Pot

Genetic analysis has revealed that the ancestors of modern humans interbred with at least five different archaic human groups as they moved out of Africa and across Eurasia. Researchers have mapped the location of past “mixing events” (analyzed from existing scientific literature) by contrasting the levels of archaic ancestry in the genomes of present-day populations around the world.
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The Potential and Uncertainties of Genetic Rescue

Researchers have attempted or explored the possibility of genetic rescue in several species. Now, a new paper examines the potential and uncertainties of attempting genetic rescue
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Thieving Red Algae Steal Genes From Bacteria to Cope With Environmental Stresses

Ten species of red algae stole about 1 percent of their genes from bacteria to cope with toxic metals and salt stress in hot springs, according to a study.
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“Slug” Keeps Breast Stem Cell Health in Check

A transcription factor called "Slug" keeps breast cells healthy by regulating both stem cell activity and repair of DNA damage.
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Individual Genotypes May Determine Efficacy of Alzheimer's Disease Drugs

Researchers have determined that a human gene present in 75% of the population is a key reason why a class of drugs for Alzheimer's disease seemed promising in animal studies only to fail in human studies. In different Alzheimer's disease patients, different mechanisms may be at work that determine whether or not a given therapy will be effective.
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“Semi-synthetic” Bacteria Churn Out Proteins Containing Unnatural Amino Acids

Researchers have optimized a semi-synthetic bacteria to efficiently produce proteins containing unnatural amino acids.
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The Human Genome Goes Wireless

It seems like everything is going wireless these days. That now includes efforts to reprogram the human genome.
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Protein Gives Identical Cells Individuality

New insight into a protein's role in regulating tight DNA packing could have implications for combating tumor cell resistance to anti-cancer treatments.
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