News

Algorithm stitches multiple datasets into a single “panorama” which could provide new insights for medical and biological studies.

The customizable approach relies on just two proteins: The first is activated in the presence of an “always on” growth signal often found in cancer cells, and the second carries out a researcher-programmed response, such as triggering the expression of genes involved in cell death.

A newly identified epigenetic hotspot for schizophrenia and bipolar disorder may give scientists a fresh path forward for devising more effective treatments and biomarker-based screening strategies.

The combination of a big population, good genes and luck helps explain how a species of fish in Texas' Houston Ship Channel was able to adapt to what normally would be lethal levels of toxins for most other species.

Researchers have used a novel approach to identify specific amino acids in the protein structure of HIV that appear critical to the ability of the virus to function and replicate.

A newly discovered relationship between genetic variation and the gut microbiome could help nutritionists personalize their recommendations.

Why do you swig bitter, dark roast coffee or hoppy beer while your coworker guzzles sweet cola? Scientists searched for variations in our taste genes that could explain our beverage preferences, because understanding those preferences could indicate ways to intervene in people's diets.

More than genes themselves, how, where and when they are expressed determine our biological traits – our phenotypes. If gene expression is controlled by many regulatory elements, what, ultimately, controls those? And how does genetic variation affect them?

Researchers have discovered a new genetic defect which causes a form of intellectual disability; a finding that will improve screening programmes and help to end a 'diagnostic odyssey' for families across the globe.

"We found that deleting the ATDC gene in pancreatic cells resulted in one of the most profound blocks of tumor formation ever observed in a well-known mice model engineered to develop pancreatic ductal adenocarcinoma... which faithfully mimics the human disease," says corresponding author Diane Simeone.