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New research has revealed how the famous tumour suppressor gene p53 is surprisingly critical for development of the neural tube in female embryos.

Tumors are a complex mixture of many different cell types, including immune cells known collectively as tumor-infiltrating myeloid cells. These cells represent alternative targets for immunotherapy, but their role in tumors is still poorly understood. To shed light on this under-examined family of immune cells, researchers used single-cell sequencing to map the landscape of myeloid cells in tumors from patients with lung cancer.

An eight-year hunt for the cells that drive an extreme childhood food allergy (eosinophilic esophagitis, EoE) has identified a potential new way to treat the disease while also raising questions about a dietary supplement often taken to reduce bowel inflammation.

Researchers provide the first summary of the experimental evidence supporting the AKR1B10 enzyme as a promising therapeutic target for the most common form of liver cancer, based on a review of more than 50 studies published since this gene was first identified and characterized in 1998.

Scientists have begun making "metal-organic frameworks" made of building blocks that typically make up biomolecules, e.g. amino acids for proteins or nucleic acids for DNA. Apart from the traditional MOF use in chemical catalysis, these biologically derived MOFs can be also used as models for complex biomolecules that are difficult to isolate and study with other means.

An international consortium has sequenced the entire genome of durum wheat--the source of semolina for pasta, a food staple for the world's population.

A new Tel Aviv University study suggests that the genetic profiles of two extinct mammals with African ancestry -- woolly mammoths, elephant-like animals that evolved in the arctic peninsula of Eurasia around 600,000 years ago, and Neanderthals, highly skilled early humans who evolved in Europe around 400,000 years ago -- shared molecular characteristics of adaptation to cold environments

A collaborative international team has unveiled a new CRISPR-based tool that acts more like a shredder, able to wipe out long stretches of DNA in human cells with programmable targeting.

Patients with colorectal cancer have the same consistent changes in the gut bacteria across continents, cultures, and diets.

Patients with colorectal cancer have the same consistent changes in the gut bacteria across continents, cultures, and diets.