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Plant Versus Pathogen
A team has identified a regulatory, genetic mechanism in plants that could help fight bacterial infection and could lead to better strategies for protecting crops from attacks by pathogens.
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MicroRNA Behind Unchecked Growth of Aggressive Liver Cancer
A non-coding microRNA has been identified as a critical brake in the regulation of a rare aggressive liver cancer. MicroRNA-375 is lost in people with the tumor, highlighting a new target for therapy development.
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Parade Gene Controls Pigment Stem Cells in Zebrafish
The abnormal positioning of pigment cells near the main blood vessels of some zebra fish has been traced back to the "parade" gene.
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Building an Atlas of Acute Myeloid Leukemia
A team of researchers has used single-cell technologies and machine learning to create a detailed "atlas of cell states" for acute myeloid leukemia that could help improve treatment of the aggressive cancer.
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Tool Reveals Molecular Causes of Disease Including Infant Cancer
Princeton University researchers are gaining new insights into the causes and characteristics of diseases by harnessing machine learning to analyze molecular patterns across hundreds of diseases simultaneously.
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New Risk Genes for Alzheimer’s Disease
Analysis of genetic data from more than 94,000 individuals has revealed five new risk genes for Alzheimer's disease, and confirmed 20 known others.
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DNA Repair: Fishing in the Protein Pond With Histone Bait
When DNA in the cell nucleus gets damaged, our cells can resort to a variety of repair mechanisms. A recent study elucidates the molecular basis by which a cell makes the choice between these repair mechanisms.
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Cell Atlas of the Aging Lung
Aging promotes lung function decline and increases susceptibility to diseases of the respiratory tract. In order to understand these effects in detail, researchers have analyzed the aging process in the lung at single-cell level, using AI approaches.
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Going Fishing in the Protein Pond Using Histones as Bait
Researchers have developed a molecular bait to fish out the relevant proteins from the cell nucleus. According to the authors, this study opens up new possibilities for cancer therapies in the future.
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Incredible Microbial Diversity in "Inhospitable" Locations
A sapphire blue hot spring 8,600 feet above sea level on the Continental Divide, where volcanic gases rise to mix with snowmelt and rainwater, is home to exceptionally diverse microbes.
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