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Great White Shark Genome Decoded
In a major scientific step to understand the biology of this iconic apex predator and sharks in general, the entire genome of the white shark has now been decoded in detail.
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One Year Later: CRISPR Success in Duchenne Muscular Dystrophy Model
Researchers have shown that a single systemic treatment using CRISPR genome editing technology can safely and stably correct a genetic disease -- Duchenne muscular dystrophy (DMD) -- for more than a year in mice, despite observed immune responses and alternative gene editing outcomes.
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Can Fear Memories Be Extinguished?
Researchers have discovered a DNA modification that enhances our ability to extinguish fear. The findings could help guide the development of new treatments for fear-related anxiety disorders.
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CRISPR Engineered “Invisible” Immune Cells
Scientists have used the CRISPR-Cas9 gene-editing system to create the first pluripotent stem cells that are functionally "invisible" to the immune system, a feat of biological engineering that, in laboratory studies, prevented rejection of stem cell transplants.
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Pumped Breast Milk Vs Direct Feeding - Important Microbiota Differences
The method of breastfeeding — directly at the breast or fed pumped breastmilk from a bottle—was the most consistent factor associated with the milk microbiota composition.
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RNA Captured Interacting With Stress Granules
Individual RNA molecules have been captured interacting with stress granules, revealing how, when and where the RNAs move around – a process never before witnessed from start to finish.
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Novel Binding Site for Anti-cancer Drugs
A research team at the Medical University of South Carolina (MUSC) has discovered a new mechanism for a class of anti-cancer drugs known as E1 inhibitors.
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Honeybee’s “Clean” Genes
Some worker honeybees detect and remove sick and dead larvae and pupae from their colonies. This hygienic behaviour, which has a strong genetic component, is known to improve the colony's chance of survival. Researchers narrowed in on the "clean" genes that influence this behaviour to understand the evolution of this unique trait.
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Prefer Menthol to Regular Cigarettes? It May Be Your Genetics
A genetic variant found only in people of African descent significantly increases a smoker's preference for cigarettes containing menthol, a flavor additive.
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Resistant Melanoma Sensitized to Cytotoxic T Cells with BRAF-targeting
BRAF-targeted therapies render resistant melanoma more sensitive to the attack of killer T cells. The findings pave the way in developing therapy for patients that have become resistant to BRAF inhibitors.
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