News

Researchers have found a way to sequence a large portion of the Y chromosome in the fruit fly Drosophila melanogaster--the most that the Y chromosome has been assembled in fruit flies.

A research team is reporting that a possible cure for addiction may be found by following the pathways of significantly altered dopamine neurons in newborns who were chronically exposed to nicotine in utero.

Bariatric surgery alters patterns of digestion and absorption lower in the gut triggering production of higher levels of gut hormones, altering the way the gut senses food and nutrients.

Work shows that T regulatory cells have tissue-specific receptors and other adaptations, which allow them to move to and remain in the correct location in the body. This could allow targeting of therapeutic cells to specific places.

Using a leading-edge technique, researchers define the cell types in both newborn and adult human testes, opening a path for new strategies to treat male infertility with stem cells.

Researchers suggests that some anti-CRISPR proteins are more widespread in nature than previously anticipated. These anti-CRISPRs can potentially be used to regulate the activity of CRISPR-Cas9 systems better in the future.

While the neural architecture responsible for the transmission of electrical impulses has been known for more than a century, the basic biology behind how a neuron acquires its one and only axon remains a mystery. Now, researchers have described the genetic switches that ignite axon formation. Their work focuses on two molecular components — polypyrimidine tract binding protein 2 and the shootin gene.

A research team has described the first case of a patient affected by dysfunctions in a nucleoside transporter of the SLC28 gene family, which brings a set of genes which were not related to human pathologies in the scientific bibliography so far

A new gene-editing protein, CasX, may give CRISPR-Cas9 a run for its money. Scientists have determined the unique structure of CasX, revealing that this pint-sized Cas enzyme is dominated by RNA that directs it to specific sequences of DNA, where it binds and cuts the DNA.

A computational method, “CATCH”, can design molecular “baits” for any virus known to infect humans, including those present in low abundance such as Zika. The approach could aid disease surveillance and help to control outbreaks.