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CRISPR Technique Refined for Potential Application in Muscular Dystrophy

Research team identify and conquer a barrier in CRISPR gene editing that may lay the foundation for sustained treatments using the technique.
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Understanding Infectious Disease by Studying Bacterial Immunity

Pseudomonas aeruginosa, a cause of serious lung infections in cystic fibrosis patients, was used as a “model system” for understanding how bacteria’s interactions with viruses may affect human health.
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Errant Editing Enzyme Promotes Tumor Suppressor Loss and Leukemia Propagation

Detection of 'copy editing' by a stem cell enzyme called ADAR1 (active in more than 20 tumor types) may act as a molecular radar for early detection of malignancies, and represent a new therapeutic target.
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Mechanism of Gene Regulation Linked to Tumor Progression

Researchers at the Centre for Genomic Regulation (CRG), have discovered a new mechanism controlling the expression of a set of genes important for cell proliferation and tumour progression.
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CRISPR Method Supresses Fertility in Agricultural Pests

Using the CRISPR gene editing tool, researchers devise a method of altering key genes that control insect sex determination and fertility.
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Genetically Engineered Spicy Tomatoes

With the latest gene-editing techniques, it could be possible, although challenging, to make a tomato produce capsaicinoids.
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Community-acquired MRSA Reveals Evolutionary Drivers

Identification of the recent spread of community-acquired MRSA in a Brooklyn religious enclave is helping experts better understand how certain high-risk populations can drive the evolution of antimicrobial resistance and identify steps that can be taken to curtail its spread.
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CRISPR for Conditional Gene Regulation

A team of engineers have developed a method to use CRISPR/Cas9 technology to set off a cascade of activities in cells, a phenomenon known as conditional gene regulation.
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Cracking the CRISPR Code

Scientists at the Francis Crick Institute discover a set of simple rules that determine the precision of CRISPR/Cas9 genome editing in human cells.
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Citrus Fruit: The Ancient Acidless Mutation

Genetic detective work illuminates the important role of Jewish culture in the widespread adoption of citrus fruit by early Mediterranean societies.
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