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Cancer Vaccine Progress: Potentially Rich Source of Tumor Specific Antigens Identified
The immunogenicity and efficacy of tumor specific antigen vaccination for select antigens has been validated in mouse models of cancer. The researchers believe that clinical trials for human cancer vaccines could start within the next 2-3 years.
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Revealing Insights: Rust Resistance in Wheat
Researchers from Aarhus University have contributed to creating new knowledge about resistance to yellow rust, which is a serious fungal disease in wheat. The results can have global importance.
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Boosting Crop Genetic Diversity by Inactivating Genes
Researchers from CIRAD and INRA recently showed that inactivating a gene, RECQ4, leads to a three-fold increase in recombination in crops such as rice, pea and tomato.
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Epigenetic Map Paves the Way for Therapeutics to Combat Hearing Loss
A team has now created the first map of "methylation" — one of the body's main epigenetic signals — that reflects the functioning of the inner ear in its entirety.
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Honeybee Protein Keeps Stem Cells Youthful
An active protein component of royal jelly helps honeybees create new queens. Stanford researchers have identified a similar protein in mammals, which keeps cultured embryonic stem cells pluripotent.
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Our Microbes Are Running the Show
The interactions that take place between the species of microbes living in the gastrointestinal system often have large and unpredicted effects on health.
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Dynamics of Chromatin During Organ and Tissue Regeneration
Researchers have analyzed the transcriptome of imaginal disks in the Drosophila melanogaster’s wing in different regeneration time periods. Through the analysis of massive RNA sequencing, they identified those genes that are differentially expressed during the process.
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Universal Cancer Test: One Test to Diagnose Them All?
A diagnostic test is in the works to identify patterns of methyl groups, which are altered dramatically by cancer. The test uses gold nanoparticles that instantly change color and indicate if the nanostructures of cancer DNA are present.
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Nanoscale Tweezers Can Perform Single-molecule 'Biopsies'
Newly-developed "nano-tweezers" created by university researchers can for the first time extract single molecules from live cells without destroying them – solving a long-standing research problem.
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Fighting Relapsed Blood Cancer with Genetically Engineered Immune Cells
University of North Carolina Lineberger Comprehensive Cancer Center researchers reported promising early results from a clinical study of an investigational cellular immunotherapy that used a patient’s own, genetically engineered immune cells to recognize and fight Hodgkin and non-Hodgkin lymphoma cells.
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