News

The most comprehensive genome-wide association study, or GWAS, of colorectal cancer risk to date, published in Nature Genetics, has discovered 40 new genetic variants and validated 55 previously identified variants that signal an increased risk of colon cancer.

An innovative approach has been used to identify thousands of antibiotic resistance genes found in bacteria that inhabit the human gut.

The bacterial protein Cas10 is usually harmless, but transforms into an enzymatic assassin when confronted with foreign genetic material.

Researchers have shown that cancer cells do not necessarily have more changes in the DNA than healthy cells. The number of changes appears to be less relevant than the location in the DNA, according to research by Ruben van Boxtel.

Scientists have uncovered that an emerging gene therapy for Parkinson’s disease creates new circuits in the brain associated with improved motor movement. These findings explain the therapeutic mechanisms involved in the emerging Parkinson’s gene therapy called AAV2-GAD.

Researchers have adapted a revolutionary new technology called single-cell RNA sequencing to study gene expression in individual cells.

Over the course of a lifespan, from conception to death, each person encounters a wide variety of environmental stressors such as pollution, tobacco smoke, the sun’s rays, pharmaceutical agents and some constituents of food. Evidence of the exposure and a person’s ability to metabolize these stressors is all hiding in the urine.

Children who are genetically predisposed to overweight, due to common gene variants, can still lose weight by changing their diet and exercise habits. Around 750 children and adolescents with overweight or obesity undergoing lifestyle intervention participated in the study conducted by researchers from the University of Copenhagen and Holbæk Hospital.

Scientists at the University have successfully applied a new way to screen the genetics of cattle embryos, based on technology originally developed for human IVF.

Individuals with a particular genetic factor may be more resistant to plaque build-up and have a reduced risk for coronary artery disease.