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10-20% of Cells in a Kidney Organoid Found to be Non-Renal
Single-cell transcriptomics revealed 10-20% of cells in a kidney organoid were non-renal cells.
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Rooting in the Genomes of Giants
Giant virus genomes have been discovered for the first time in a forest soil ecosystem.
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Autism Gene Makes Mouse Brains Less Flexible
About 1% of patients diagnosed with autism spectrum disorder and intellectual disability have a mutation in a gene called SETD5. Scientists have now discovered what happens on a molecular level when the gene is mutated in mice, and how this changes the mice’s behavior.
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Molecule Fights Muscular Paralysis
UNIGE researchers have identified a molecule that can halt the progress of a severe genetic disease that causes whole-body muscle paralysis followed by death.
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Gene Editing Dramatically Improves Inherited Kidney Disease in Mice
Gene editing could be used to stop kidney damage in patients who have Joubert syndrome, an inherited kidney disease.
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Pancreatic Cancer: Mechanism of treatment-resistance discovered
Despite decades of research, treatments that can target a common mutation in the most frequently diagnosed type of pancreatic cancer have remained elusive. Now, researchers report they have discovered a mechanism of resistance to a treatment they’d identified as promising.
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Human Cell Atlas Study Sheds Light on Maternal-Fetal Interface
The first Human Cell Atlas study of early pregnancy in humans has shown how the function of the maternal immune system is affected by cells from the developing placenta.
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Breeding Corn for Water-use Efficiency May Have Just Gotten Easier
With approximately 80 percent of our nation's water supply going towards agriculture, it's fair to say it takes a lot of water to grow crops. In a climate with less predictable rainfall patterns and more intense droughts, scientists are working to reduce water consumption by developing more efficient crops.
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Symbiosis a Driver of Truffle Diversity
While the sight of black or white truffle being shaved over on pasta is generally considered a sign of dining extravagance, they play an important role in soil ecosystem services. Researchers have now conducted a comparative analysis of eight Pezizomycete fungi, including four species prized as delicacies.
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Blood Test Detects and Classifies Cancer at its Earliest Stages
Cancer scientists have combined "liquid biopsy," epigenetic alterations and machine learning to develop a blood test to detect and classify cancer at its earliest stages.
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