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Neuropathological Gene Shows Altered Lipid Metabolism
Pathway identified which affects stress-induced lipid metabolism, implicates epigenetic dysregulation in relevant human diseases.
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Virus Production Boosted to Generate More Vectors for Gene Transfer
New method increases the released lentiviral particles produced by host cells, which will aid the use of the vectors for introducing foreign genes.
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Sweet Discovery in Chocolate's Tasty Past
As Halloween revelers prepare to feast on chocolate, a new study is pushing back the origins of the delicious sweet treat.
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Cancer’s Most Deadly Assassin Exists in Every Cell
A kill code is embedded in every cell in the body whose function may be to cause the self-destruction of cells that become cancerous, reports a new Northwestern Medicine study.
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Screening Pipeline Maps Protein-RNA Interactions
A screening pipeline capable of detecting interactions within protein libraries or between protein libraries and RNA fragment pools has been developed to improve understanding of cellular mechanisms.
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Earlham's Aequatus Tool Enables Homologous Gene Comparison
Aequatus - a new bioinformatics tool developed at Earlham Institute (EI) - is helping to give an in-depth view of syntenic information between different species, providing a system to better identify important, positively-selected, and evolutionarily-conserved regions of DNA.
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Tetracyclines Found in Cellular Hide and Seek
The intricate quest to discover where tetracyclines go in human cells is over, helping to understand the promising results shown in their use to treat pathological inflammation and cancer.
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BASF licenses CRISPR-Cpf1 from the Broad Institute of MIT and Harvard
The chemical company BASF has attained a global, non-exclusive licensing agreement with the Broad Institute of MIT and Harvard for the use of CRISPR-Cpf1 genome editing technology to improve products in agricultural and industrial microbiology applications.
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Targeted Drug Could Slow Ovarian Cancer Progression in Women with Faulty BRCA Gene
A drug could help slow the progression of some advanced ovarian cancers and extend the time that patients show no signs of disease, according to new clinical trial results.
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Epigenetic Drug Strategy to Treat Cancer
Researchers have discovered that inhibiting CDK9, a DNA transcription regulator, reactivates genes that have been epigenetically silenced by cancer.
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