$3.6 Million to Study Adverse Effects of Genome EditingNews
As genome editing technologies advance toward clinical therapies, they are raising hopes of a completely new way to treat disease. However, challenges need to be addressed before potential treatments can be widely used in patients. To tackle these challenges, the National Institutes of Health has launched the Somatic Cell Genome Editing program, which has awarded multiple grants including more than $3.6 million to assess the safety of genome editing in human cells and tissues.
Comparing two strains of Salmonella – one that causes disease in humans and the other in reptiles – researchers discovered a covert way that the human-affecting bacteria essentially tricks the immune system into not attacking.READ MORE
A pioneer in the study of neural cells has revealed how a single mutation affecting the most common protein in a supporting brain cell produces devastating, fibrous globs. These, in turn, disturb the location of cellular processing units, harm the flow of energy and signals through the brain, and reduce the formation of myelin, an essential insulator for neurons.
Pioneering research into the mechanisms controlling gene activity and epigenetic factors in the brain could hold the key to understanding Alzheimer’s disease and might help identify effective treatments in the future.
Now available in Europe: A diagnostic test which can simultaneously detect tuberculosis-causing bacteria and determine if the bacteria contain mutations associated with resistance to two important first line drugs.READ MORE
Previous work by the International Multiple Sclerosis Genetics Consortium (IMSGC) has identified 233 genetic risk variants. However, these only account for about 20% of overall disease risk, with the remaining genetic culprits proving elusive. A new study has tracked down four of these hard-to-find genes.READ MORE
Researchers have succeeded in using CRISPR-Cas9, to decrease mosquito body size, moving the research one step closer to eliminating mosquitoes that carry dengue fever and Zika virus.READ MORE
Babies that are breastfed for at least six months have less antibiotic-resistant bacteria in their gut compared with infants breastfed for a shorter time.READ MORE
Accurately predicting which subtype of Crohn's disease is likely to develop has not been possible, until now.READ MORE