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CRISPR Heals Mouse Genomic Disease
A team of researchers from ETH Zurich and the University Children’s Hospital Zurich applied a newly developed editing tool to target and correct genetic mutations. By doing so, the researchers healed mice suffering from a genetic metabolic disorder that also affects humans.
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Why Sharks are Genomic "Living Fossils"
Scientists have decoded the whole genomes of two shark species for the first time and improved the whale shark genome sequences released previously. By analyzing the genomes and comparing them with those of other vertebrate species, they have constructed an overview of their unique life histories and evolutionary paths.
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Epigenetic Profiling Improved by Using Enzyme, Rather than Chemical, Deamination
A new method for sequencing the chemical groups attached to the surface of DNA is paving the way for better detection of cancer and other diseases.
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Gene Signature Could Predict Recovery After Spinal Cord Injury
A new study claims to have determined a gene signature that is linked to the severity of spinal cord injury in animals and humans. The discovery of key genes that are switched on or off in response to spinal cord injury could inform the development of biomarkers that predict recovery and possibly pinpoint new targets for treatment.
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Nanopore Technology Detects Small Lung Cell Cancer MicroRNA
Nanopore technology with DNA computing easily detects microRNA patterns of lung cancer.
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What Keeps Chromosomes in Check During Meiosis?
One of the worst things that can happen to a cell is to end up with the wrong number of chromosomes. This can happen if something goes wrong during cell division, and it can lead to infertility, miscarriages, birth defects, or cancer. An estimated 30 percent of miscarriages are due to an incorrect number of chromosomes in the cells of the embryo.
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Why Huskies Have Blue Eyes
DNA testing of more than 6,000 dogs has revealed that a duplication on canine chromosome 18 is strongly associated with blue eyes in Siberian Huskies. According to the authors, this represents the first consumer genomics study ever conducted in a non-human model and the largest canine genome-wide association study to date.
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How Baby Giraffes Inherit Their Spots
Some features of a giraffe’s spot pattern are passed on from mother to baby, according to a new study led by researchers from Penn State. The study also reveals that survival of young giraffes is related to spot pattern, which may help provide camouflage from predators.
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Single-Cell Analysis Reveals Stem Cell Journey in the Heart
Fundamental mechanisms underlying heart development and differentiation have been mapped out, thanks to extensive single-cell transcriptomic analyses.
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Japanese Insect Delicacy Genome Sequenced
Japanese scientists have shed light on the evolutionary biology and distribution of Stenopsyche caddisflies, also known as sedge flies, a common insect in Japanese rivers and a local delicacy. The new discovery also identified new genetic lineages among previously recognized species.
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